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Ann Thorac Surg 2005;80:647-654
© 2005 The Society of Thoracic Surgeons

Original article: Cardiovascular

Results of Aortic Valve-Sparing and Restoration With Autologous Pericardial Leaflet Extensions in Congenital Heart Disease

Jonah Odim, MD, PhD, MBA * , Hillel Laks, MD, Vivek Allada, MD, John Child, MD, Stacy Wilson, BS, David Gjertson, PhD

Division of Cardiothoracic Surgery, Pediatric Cardiology and Ahmanson, University of California, Los Angeles Adult Congenital Heart Disease Center, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California

Accepted for publication March 4, 2005.

* Address reprint requests to Dr Odim, Division of Cardiothoracic Surgery, David Geffen School of Medicine at UCLA, Room 62-266B, 10833 Le Conte Ave, Los Angeles, CA 90095-1741 (Email: jodim{at}mednet.ucla.edu).

Presented at the Fortieth Annual Meeting of The Society of Thoracic Surgeons, San Antonio, TX, Jan 26–28, 2004.

BACKGROUND: The purpose of this study is to evaluate the efficacy of aortic valve-sparing repair with glutaraldehyde-treated autologous pericardium in congenital valvular pathology.

METHODS: Sixty-two patients underwent reparative aortic valve surgery from January 1997 through December 2003. The mean age was 25 ± 20 years (± standard deviation) (range, 10 days to 81 years). Fifty percent (31 of 62) were less than 19 years old at operation. The diagnoses included bicuspid aortic valve (39 patients), ventricular septal defect (14 patients), severe aortic stenosis (6 patients), subaortic stenosis (7 patients), bacterial endocarditis (7 patients), neonatal truncus arteriosus (2 patients), Shone’s complex (2 patients), transposition complex (1 patient), double-chambered right ventricle (1 patient), and Marfan’s syndrome (1 patient). Twelve patients (19 %) had prior sternotomy and cardiac operations. Valve-sparing techniques included pericardial leaflet extensions in 62 patients, creation of one or more pericardial neoaortic sinuses in 8, subcommissuroplasty in 8, pericardial patch of perforated leaflets in 9, Dacron mesh wrap (Boston Scientific, Wayne, NJ) of dilated ascending aorta in 12, and concomitant tricuspid and mitral valve repairs in 3 and 4 patients, respectively.

RESULTS: There was one early death (1.6%). There were no late deaths at a mean follow-up of 25 ± 16 (range, 0.1 to 72.5 months). Six patients required reoperation and prosthetic or homograft replacement for aortic valve incompetence. One out of 6 reoperations required re-repair. The remaining patients are well with a mean aortic regurgitation grade by echocardiography of 1.3 ± 0.9 (scale, 0 to 4).

CONCLUSIONS: Aortic valve repair with pericardial leaflet extension is a promising technique for the growing child.




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