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Ann Thorac Surg 2005;80:548-552
© 2005 The Society of Thoracic Surgeons

Original article: Cardiovascular

CardioWest Total Artificial Heart: Bad Oeynhausen Experience

Aly El-Banayosy, MD * , Latif Arusoglu, MD, Michel Morshuis, MD, Lukasz Kizner, MD, Gero Tenderich, MD, Peter Sarnowski, RN, Hendrik Milting, PhD, Reiner Koerfer, MD, PhD

Department of Thoracic and Cardiovasular Surgery, Heart Center North Rhine-Westphalia, Ruhr University Bochum, Bad Oeynhausen, Germany

Accepted for publication February 28, 2005.

* Address reprint requests to Dr El-Banayosy, Klinik für Thorax und Kardiovaskularchirurgie, Herzzentrum NRW, Georgstr. 11, 32545 Bad Oeynhausen, Germany (Email: abanayosy{at}hdz-nrw.de).

BACKGROUND: The use of ventricular assist devices (VAD) has become a widely accepted therapeutic option. However, there are still limitations to the patient collective eligible for VAD placement, who might therefore benefit from the implantation of a total artificial heart. We present the first German single-center experience with the CardioWest total artificial heart (TAH) (SynCardia Systems, Tucson, AZ) in 42 patients.

METHODS: Between February 2001 and December 2003, 42 patients (37 men, 5 women, mean age 51 ± 13 years) received a TAH at our Center. Their body surface area ranged between 1.5 and 2.4 (mean, 1.9 ± 0.19) m2. All patients were in persistent cardiogenic shock in spite of maximum inotropic support and had numerous preoperative risk factors (intraaortic balloon pumping, mechanical ventilation, acute renal failure, previous cardiac surgery, recent cardiopulmonary resuscitation).

RESULTS: Duration of support was 1 to 291 days. Eleven patients (26%) underwent successful transplantation; 9 of them could be discharged home. Twenty-two patients died under support, 21 of them from multiple organ failure and 1 patient from a technical problem. Nine patients are still on the device, 4 of them at home after the original CardioWest console was replaced by the Berlin Heart EXCOR driver (Berlin Heart, Berlin, Germany). Exceptional results were achieved in patients with cardiogenic shock after cardiac surgery or after acute myocardial infarction.

CONCLUSIONS: Against the background of the extremely poor preoperative situation of our patients, the overall survival rate of 48% can be considered as favorable. A prospective, randomized study is planned to find out whether patients with idiopathic dilated or ischemic cardiomyopathy are more likely to benefit from a biventricular assist device or a total artificial heart.




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