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Ann Thorac Surg 2005;79:1409-1411
© 2005 The Society of Thoracic Surgeons

Case report

A Direct Measurement of Serum Amylase Levels Produced by Lung Cancer

Mitsuaki Sakai, MD*,a, Shigemi Ishikawa, MD, PhDb, Tatsuo Yamamoto, MD, PhDb, Masataka Onizuka, MD, PhDb, Yuzuru Sakakibara, MD, PhDb, Masayuki Noguchi, MD, PhDc

a Department of Thoracic Surgery, Tsukuba Gakuen Hospital, Tsukuba, Ibaraki, Japan
b Department of Surgery, Institute of Clinical Medicine, Tsukuba, Ibaraki, Japan
c Department of Pathology, Institute of Basic Medical Science, University of Tsukuba, Tsukuba, Ibaraki, Japan

Accepted for publication October 16, 2003.

* Address reprint requests to Dr Sakai, Tsukuba University Hospital, Department of Thoracic Surgery, Amakubo 2-1-1, Tsukuba City, Ibaraki Prefecture 305-8576, Japan
misakai-ths{at}umin.ac.jp

The production of amylase by lung cancer has been previously diagnosed pathologically or immunohistochemically, or it has been confirmed by a decrease in serum levels after resection. It is possible to directly probe the continuous production of amylase by collecting samples from the inflow and outflow vessels of lung cancer. We herein describe an intraoperative measurement in which the amylase level in the pulmonary lobar vein was 3 times greater than that in the superior vena cava which was 6 times greater than the normal range. The venous level of amylase returned to a normal range after resection.






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