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Right arrow Lung - transplantation

Ann Thorac Surg 2005;79:1051-1052
© 2005 The Society of Thoracic Surgeons

Case report

Living-Donor Lobar Lung Transplantation for Bronchiolitis Obliterans After Bone Marrow Transplantation

Yoshifumi Sano, MDa,*, Hiroshi Date, MDa, Itaru Nagahiro, MDa, Motoi Aoe, MDa, Nobuyoshi Shimizu, MDa

a Department of Cancer and Thoracic Surgery, Okayama University Graduate School of Medicine and Dentistry, Okayama, Japan

Accepted for publication September 10, 2003.

* Address reprint requests to Dr Sano, Department of Cancer and Thoracic Surgery, Okayama University Graduate School of Medicine and Dentistry, 2-5-1 Shikata-cho, Okayama 700-8558, Japan
ysano{at}md.okayama-u.ac.jp

We report a successful case of living-donor lobar lung transplantation (LDLLT) for severe bronchiolitis obliterans (BO) after bone marrow transplantation (BMT). The patient is a 29-year-old woman who underwent BMT because of aplastic anemia in 1995. In 1996, BO developed in the patient because of chronic graft-versus-host disease. In May 2000, a LDLLT was performed. Pulmonary function tests showed improvement of both vital capacity and forced expiratory volume in 1 second. At present, 91 months after BMT and 38 months after lung transplantation, the patient is in good health. LDLLT may offer a therapeutic option for the treatment of BO after BMT.




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A. O. Soubani and J. P. Uberti
Bronchiolitis obliterans following haematopoietic stem cell transplantation
Eur. Respir. J., May 1, 2007; 29(5): 1007 - 1019.
[Abstract] [Full Text] [PDF]


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