| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Ann Thorac Surg 2005;79:411-416
© 2005 The Society of Thoracic Surgeons
a Department of Thoracic Surgery, University of Rome "La Sapienza," Rome, Italy
b Department of Pulmonology, University of Rome "La Sapienza," Rome, Italy
Accepted for publication July 19, 2004.
* Address reprint requests to Dr Venuta, University of Rome "La Sapienza," Department of Thoracic Surgery, Policlinico Umberto I, V.le del Policlinico, 00100 Rome, Italy (E-mail: sofed{at}libero.it).
BACKGROUND: We evaluated the feasibility and short-term functional outcome after bronchoscopic lung-volume reduction performed with one-way valves in patients with severe heterogeneous emphysema.
METHODS: Thirteen patients entered this pilot study. Endobronchial one-way valves were placed in the segmental bronchi supplying the most hyperinflated parts of the emphysematous lungs to allow lung deflation, reduce lung volume, and alleviate symptoms. The valves and delivery catheter were inserted under intravenous anesthesia and spontaneous assisted ventilation, with visual control through a flexible bronchoscope. We performed unilateral bronchoscopic lung-volume reduction in 11 patients and staged bilateral procedures in 2. Preoperative median forced expiratory volume in 1 second (FEV1) was 0.75 L/s (22%), residual volume was 5.3 L (233%), total lung capacity, 7.9 L (123%); intrathoracic gas volume, 6.5 L (176%); and 6-minute walk test, 223 meters. All patients required supplemental oxygen at rest (1.4 L/min). The median preoperative Medical Research Council (MRC) scale dyspnea score was 4.
RESULTS: Six complications occurred in 3 patients: two bilateral and one contralateral pneumothorax, one pneumonia, and two episodes of bronchospasm. Functional results at 1 and 3 months showed a significant improvement in FEV1, residual volume, and 6-minute walk test; 43% of the patients were able to completely stop supplemental oxygen. The posttreatment MRC median dyspnea score at 1 and 3 months was 2. Bronchoscopic follow up at 1 and 3 months showed that the valves were correctly in place with no granulation.
CONCLUSIONS: Bronchoscopic lung-volume reduction with one-way valves can be performed with acceptable short-term safety and worthwhile functional benefits.
This article has been cited by other articles:
|
|
 |
|
  A. D'Andrilli, L. Vismara, M. Rolla, M. Ibrahim, F. Venuta, I. Pochesci, R. Masciangelo, and E. A. Rendina Computed tomography with volume rendering for the evaluation of parenchymal hyperinflation after bronchoscopic lung volume reduction Eur. J. Cardiothorac. Surg., March 1, 2009; 35(3): 403 - 407. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. M. Chan, F. J. Martinez, and A. C. Chang Nonmedical Therapy for Chronic Obstructive Pulmonary Disease Proceedings of the ATS, January 15, 2009; 6(1): 137 - 145. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. O. Coxson, P. V. Nasute Fauerbach, C. Storness-Bliss, N. L. Muller, S. Cogswell, D. H. Dillard, C. L. Finger, and S. C. Springmeyer Computed tomography assessment of lung volume changes after bronchial valve treatment Eur. Respir. J., December 1, 2008; 32(6): 1443 - 1450. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. P. Ingenito, D. E. Wood, and J. P. Utz Bronchoscopic Lung Volume Reduction in Severe Emphysema Proceedings of the ATS, May 1, 2008; 5(4): 454 - 460. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. Venuta, E. A. Rendina, T. De Giacomo, and G. F. Coloni Bronchoscopic lung volume reduction MMCTS, December 17, 2007; 2007(1217): 2121. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. F.G. Cardoso, G. I. Snell, P. Hopkins, G. W. Sybrecht, G. Stamatis, A. W. Ng, and P. Eng Clinical application of airway bypass with paclitaxel-eluting stents: Early results. J. Thorac. Cardiovasc. Surg., October 1, 2007; 134(4): 974 - 981. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Bhattacharyya, D. Sarkar, S. Nag, S. Ghosh, and S. Roychoudhury Transbronchial decompression of emphysematous bullae: a new therapeutic approach Eur. Respir. J., May 1, 2007; 29(5): 1003 - 1006. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. E. Wood, R. J. McKenna Jr, R. D. Yusen, D. H. Sterman, D. E. Ost, S. C. Springmeyer, H. X. Gonzalez, M. S. Mulligan, T. Gildea, W. V. Houck, et al. A multicenter trial of an intrabronchial valve for treatment of severe emphysema J. Thorac. Cardiovasc. Surg., January 1, 2007; 133(1): 65 - 73. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. I. Polkey and N. S. Hopkinson Bronchoscopic lung volume reduction Eur. Respir. Rev., December 1, 2006; 15(100): 99 - 103. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Anile, F. Venuta, T. De Giacomo, E. A. Rendina, D. Diso, F. Pugliese, F. Ruberto, and G. F. Coloni Treatment of persistent air leakage with endobronchial one-way valves. J. Thorac. Cardiovasc. Surg., September 1, 2006; 132(3): 711 - 712. [Full Text] [PDF]
|
|
|
|
 |
|
 H. G. de Oliveira, A. V. Macedo-Neto, A. B. John, S. Jungblut, J. C. Prolla, S. S. Menna-Barreto, and E. A. F. Fortis Transbronchoscopic Pulmonary Emphysema Treatment: 1-Month to 24-Month Endoscopic Follow-up. Chest, July 1, 2006; 130(1): 190 - 199. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Feller-Kopman, R. Bechara, R. Garland, A. Ernst, and S. Ashiku Use of a removable endobronchial valve for the treatment of bronchopleural fistula. Chest, July 1, 2006; 130(1): 273 - 275. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E J Cetti, A J Moore, and D M Geddes Collateral ventilation Thorax, May 1, 2006; 61(5): 371 - 373. [Full Text] [PDF]
|
|
|
|
|
|
F. Venuta, E. A. Rendina, T. De Giacomo, M. Anile, D. Diso, C. Andreetti, F. Pugliese, and G. F. Coloni Bronchoscopic procedures for emphysema treatment Eur. J. Cardiothorac. Surg., March 1, 2006; 29(3): 281 - 287. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. Y. P. Wan, T. P. Toma, D. M. Geddes, G. Snell, T. Williams, F. Venuta, and A. P. C. Yim Bronchoscopic Lung Volume Reduction for End-Stage Emphysema: Report on the First 98 Patients Chest, March 1, 2006; 129(3): 518 - 526. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. Venuta and G. Bognolo Surgery for emphysema. BMJ, February 18, 2006; 332(7538): 375 - 376. [Full Text] [PDF]
|
|
|
|
 |
|
 N. S. Hopkinson and M. I. Polkey Am. J. Respir. Crit. Care Med., January 15, 2006; 173(2): 248a - 249. [Full Text] [PDF]
|
|
|
|
|
|
T. K. Trow Clinical Year in Review I: Lung Cancer, Interventional Pulmonology, Noninvasive Mask Ventilation, and Pulmonary Vascular Disease Proceedings of the ATS, August 1, 2005; 2(2): 102 - 104. [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| ANN THORAC SURG | ASIAN CARDIOVASC THORAC ANN | EUR J CARDIOTHORAC SURG |
| J THORAC CARDIOVASC SURG | ICVTS | ALL CTSNet JOURNALS |
