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Ann Thorac Surg 2005;79:e1-e2
© 2005 The Society of Thoracic Surgeons

Case report

Multiple Ground-Glass Opacity in Metastasis of Malignant Melanoma Diagnosed by Lung Biopsy

Riki Okita, MDa,*, Motohiro Yamashita, MDa, Masao Nakata, MDa, Norihiro Teramoto, MDb, Akihiro Bessho, MDc, Hiroshi Mogami, MDd

a Department of Surgery, National Shikoku Cancer Center Hospital, Matsuyama, Japan
b Department of Pathology, National Shikoku Cancer Center Hospital, Matsuyama, Japan
c Department of Internal Medicine, National Shikoku Cancer Center Hospital, Matsuyama, Japan
d Department of Radiology, National Shikoku Cancer Center Hospital, Matsuyama, Japan

Accepted for publication March 31, 2004.

* Address reprint requests to Dr Okita, Department of Surgical Oncology, Hiroshima University, Research Institute for Radiation Biology and Medicine, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8553, Japan
rokita{at}hiroshima-u.ac.jp

Focal ground-glass opacity (GGO) on computed tomography has been reported in several disorders including inflammatory disease and primary neoplastic lesion of the lung. We report a case of malignant melanoma of the nasal cavity metastatic to the lungs in which multiple pulmonary nodules showed GGO. Lung biopsy specimen demonstrated melanoma cells proliferating in a lepidic fashion along the thickened alveolar wall simulating bronchioloalveolar carcinoma. Metastatic lung tumor showing GGO is uncommon.




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C. M. Park, J. M. Goo, T. J. Kim, H. J. Lee, K. W. Lee, C. H. Lee, Y. T. Kim, K. G. Kim, H. Y. Lee, E.-A. Park, et al.
Pulmonary Nodular Ground-Glass Opacities in Patients With Extrapulmonary Cancers: What is Their Clinical Significance and How Can We Determine Whether They Are Malignant or Benign Lesions?
Chest, June 1, 2008; 133(6): 1402 - 1409.
[Abstract] [Full Text] [PDF]


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