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Ann Thorac Surg 2004;78:2161-2163
© 2004 The Society of Thoracic Surgeons

Case report

Anterior Mediastinal Presentation of a Giant Angiomyolipoma

Afzal M.I. Amir, MDa, Clark J. Zeebregts, MD*,a, H. Jan Mulder, MD, PhDa

a Department of Surgery, Medisch Spectrum Twente, Enschede, The Netherlands

Accepted for publication August 1, 2003.

* Address reprint requests to Dr Zeebregts, Department of Vascular Surgery, University Hospital Groningen, PO Box 30.001, Groningen 9700 RB, The Netherlands
czeebregts{at}hotmail.com

Angiomyolipomas are benign, solitary, noninvasive lesions that most often arise in the kidney. Extrarenal manifestations of these tumors include the skin, oropharynx, the abdominal wall, retroperitoneum, gastrointestinal tract, heart, lung, liver, uterus, penis, and spinal cord. We report a patient with a giant angiomyolipoma located in the anterior mediastinum. We believe this is the seventh reported case of mediastinal angiomyolipoma and the largest reported by size. It is the second reported lesion to arise in the anterior mediastinum. Distinction from other pulmonary or thoracic masses relies on the appreciation of the unique and characteristic histologic features of these mediastinal angiomyolipomas. We conclude that, although rare, angiomyolipoma should be considered in the differential diagnosis of a mediastinal tumor.




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