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Ann Thorac Surg 2004;78:1453-1455
© 2004 The Society of Thoracic Surgeons

Case report

Aspergillus Endocarditis in a Native Valve After Amphotericin B Treatment

Anastasia N. Kotanidoua,*, Epaminonthas Zakynthinos, MDa, Ilias Andrianakis, MDa, Dimitrios Zervakis, MDa, Ioannis Kokotsakis, MDb, Theodoros Argyrakos, MDc, Athina Argiropoulou, MDd, Georgia Margariti, MDd, Emmanuel Douzinas, MDa

a Department of Critical Care and Pulmonary Services, University of Athens, Athens, Greece
b Department of Cardiothoracic Surgery, Athens, Greece
c Department of Pathology, Evagelismos Hospital, Athens, Greece
d Department of Microbiology, Evagelismos Hospital, Athens, Greece

Accepted for publication July 10, 2003.

* Address reprint requests to Dr Kotanidou, Department of Critical Care and Pulmonary Services, University of Athens, Ipsilantou 45-47, Athens 10675, Greece
akotanid{at}med.uoa.gr

Systemic infection with Aspergillus fumigatus is an opportunistic disease that affects mainly immunocompromised hosts and is associated with a high mortality rate. We report a case of A. fumigatus endocarditis after an episode of thrombotic thrombocytopenic purpura. Diagnosis was established after sudden rupture of posterior papillary muscle of the normal native mitral valve. Soon after mitral valve replacement, Aspergillus endocarditis recurred, associated with multiple peripheral emboli, which necessitated a second operation.




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P. Badiee, A. Alborzi, E. Shakiba, M. Ziyaeyan, and B. Pourabbas
Molecular diagnosis of Aspergillus endocarditis after cardiac surgery
J. Med. Microbiol., February 1, 2009; 58(2): 192 - 195.
[Abstract] [Full Text] [PDF]


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