HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Author home page(s): Antonio F. Corno Michel Hurni Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Corno, A. F. Articles by von Segesser, L. K. Search for Related Content PubMed PubMed Citation Articles by Corno, A. F. Articles by von Segesser, L. K. Related Collections Congenital - cyanotic

Ann Thorac Surg 2004;78:1382-1388
© 2004 The Society of Thoracic Surgeons

---

Original article: cardiovascular

Bovine Valved Xenograft in Pulmonary Position: Medium-Term Follow-Up With Excellent Hemodynamics and Freedom From Calcification

^a Department of Cardiovascular Surgery, Lausanne, Switzerland
^b Department of Radiology, Lausanne, Switzerland
^c Department of Pediatrics, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland

Accepted for publication February 10, 2004.

^* Address reprint requests to Dr Corno, Department of Cardiovascular Surgery, Centre Hospitalier Universitaire Vaudois (CHUV), 46 Rue du Bugnon, CH 1011, Lausanne, Switzerland
antonio.corno{at}chuv.hospvd.ch

Presented at the Fortieth Annual Meeting of The Society of Thoracic Surgeons, San Antonio, TX, Jan 26–28, 2004.

BACKGROUND: This study was designed to evaluate the outcome of Contegra xenograft valved conduit (Contegra, Medtronic Inc, Minneapolis, MN).

METHODS: From April 1999 to December 2003, 67 patients with a mean age of 16.1 ±15.0 years (2 months to 53 years) and a mean weight of 39.7 ± 27.1 kg (4 to 95 kg) were discharged after implantation of a Contegra conduit. The diagnosis contained the following: pulmonary valve replacement during Ross operation (n = 27), pulmonary valve regurgitation (n = 9), tetralogy of Fallot (n = 7), pulmonary atresia with ventricular septal defect (n = 7), double outlet right ventricle (n = 7), truncus arteriosus (n = 5), Taussig-Bing (n = 2), obstructed conduit (n = 2), and double discordance (n = 1). Conduit size was 14 mm in 2, 16 mm in 7, 18 mm in 12, 20 mm in 13, and 22 mm in 33 patients. Mean cardiopulmonary bypass was 155 ± 48 min (65 to 337 min) and mean aortic cross clamping was 69 ± 38 min (0 to 146 min). All patients underwent echocardiography, 23 of 67 (34%) patients had cardiac catheterization, and 23 of 67 (34%) patients had electrocardiograph-gated multislice computer tomography.

RESULTS: In a mean follow-up of 26.4 months (1 to 56 months) there was one late death (1 of 67 patients; 1.5% mortality) unrelated to the conduit. Five patients underwent reoperation; four were nonconduit-related and one was to replace a twisted conduit. Five patients underwent interventional cardiology; three were nonconduit-related and two were to stent a twisted or stenotic conduit. Echocardiography showed absent valve regurgitation in 30 of 67 (45%) patients, trivial in 21 of 67 (31%) patients, mild in 16 of 67 (24%) patients. The transconduit pressure gradient remained stable during follow-up, with peak pressure gradient 17 ± 11 mm Hg and mean gradient 8 ± 6 mm Hg. Internal diameters corresponded to 110% ± 20% of the implanted diameter at level of proximal anastomosis, 112% ± 18% at valve level, and 110% ± 14% at distal anastomosis. Calcifications were not found, with the exception of a minimal (2.3 mm) parietal calcification.

CONCLUSIONS: The Contegra valved conduit provided excellent morphology and hemodynamics, and freedom from calcification in a medium-term follow-up.

This article has been cited by other articles:

				A. F. Corno and E. S. Mickaily-Huber Comparative computational fluid dynamic study of two distal Contegra conduit anastomoses Interactive CardioVascular and Thoracic Surgery, February 1, 2008; 7(1): 1 - 5. [Abstract] [Full Text] [PDF]

				J. Sierra, J. T. Christenson, N. H. Lahlaidi, M. Beghetti, and A. Kalangos Right Ventricular Outflow Tract Reconstruction: What Conduit to Use? Homograft or Contegra? Ann. Thorac. Surg., August 1, 2007; 84(2): 606 - 611. [Abstract] [Full Text] [PDF]

				T. M. Bashore Adult Congenital Heart Disease: Right Ventricular Outflow Tract Lesions Circulation, April 10, 2007; 115(14): 1933 - 1947. [Full Text] [PDF]

				A. J. Rastan, T. Walther, I. Daehnert, J. Hambsch, F. W. Mohr, J. Janousek, and M. Kostelka Bovine jugular vein conduit for right ventricular outflow tract reconstruction: evaluation of risk factors for mid-term outcome. Ann. Thorac. Surg., October 1, 2006; 82(4): 1308 - 1315. [Abstract] [Full Text] [PDF]

				T. W. Waterbolk, E. S. Hoendermis, I. J. den Hamer, and T. Ebels Pulmonary valve replacement with a mechanical prosthesis. Promising results of 28 procedures in patients with congenital heart disease. Eur. J. Cardiothorac. Surg., July 1, 2006; 30(1): 28 - 32. [Abstract] [Full Text] [PDF]

				C. Schreiber, S. Sassen, M. Kostolny, J. Horer, J. Cleuziou, M. Wottke, K. Holper, F. Fend, A. Eicken, and R. Lange Early graft failure of small-sized porcine-valved conduits in reconstruction of the right ventricular outflow tract. Ann. Thorac. Surg., July 1, 2006; 82(1): 179 - 185. [Abstract] [Full Text] [PDF]

				H. Dave, A. Dodge-Khatami, A. Kadner, and R. Pretre Modified Technique for Heterotopic Implantation of a Right Ventricular Outflow Tract Conduit Ann. Thorac. Surg., June 1, 2006; 81(6): 2321 - 2323. [Abstract] [Full Text] [PDF]