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Right arrow Lung - transplantation

Ann Thorac Surg 2004;78:e48-e50
© 2004 The Society of Thoracic Surgeons

Case report

Aerosolized iloprost as a bridge to lung transplantation in a patient with cystic fibrosis and pulmonary hypertension

Pierre Tissières, MDa, Laurent Nicod, MDd, Constance Barazzone-Argiroffo, MDb, Peter C. Rimensberger, MDc, Maurice Beghetti, MD*,a

a Unit of Pediatric Cardiology, Geneva, Switzerland
b Unit of Pulmonary Medicine, Geneva, Switzerland
c Unit of Critical Care Medicine, Department of Pediatrics, University Children's Hospital, Geneva, Switzerland
d Division of Pulmonary Medicine, University Hospital of Geneva, Geneva, Switzerland

Accepted for publication December 29, 2003.

* Address reprint requests to Dr Beghetti, Children's Hospital of Geneva, Pediatric Cardiology Unit, 6 Rue Willy-Donzé, Geneva 14, 1211, Switzerland
maurice.beghetti{at}hcuge.ch

We describe a patient with cystic fibrosis, end-stage lung disease, and secondary pulmonary hypertension in whom aerosolized iloprost was effective in lowering pulmonary artery pressure and improving functional status, thus proving successful as a bridge to lung transplantation. Inhaled iloprost may be an efficient and selective approach to treat pulmonary hypertension related to end-stage obstructive pulmonary disease.






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