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Faisal H. Cheema
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Deon W. Vigilance
Craig R. Smith
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Ann Thorac Surg 2004;78:73-76
© 2004 The Society of Thoracic Surgeons


Original article: cardiovascular

Edge-to-edge mitral valve repair: the Columbia Presbyterian experience

Aftab R. Kherani, MDa*, Faisal H. Cheema, MDa, Jennifer Casher, BAa, Jennifer M. Fal, BAa, Christopher J. Mutrie, MDa, Jonathan M. Chen, MDa, Jeffrey A. Morgan, MDa, Deon W. Vigilance, MDa, Mauricio J. Garrido, MDa, Craig R. Smith, MDa, Mehmet C. Oz, MDa

a Department of Cardiothoracic Surgery, Columbia-Presbyterian Medical Center, New York, New York, USA

Accepted for publication August 28, 2003.

* Address reprint requests to Dr Kherani, Division of Cardiothoracic Surgery, College of Physicians and Surgeons, Columbia University, 177 Ft Washington Ave, MHB 7GN-435, New York, NY, USA 10032
e-mail: khera001{at}mc.duke.edu

BACKGROUND: The edge-to-edge mitral valve repair, first described by Alfieri in 1995 treats mitral regurgitation when standard reparative techniques are difficult, unlikely to succeed, or have failed. This study examines one institution's medium-term experience with this procedure.

METHODS: This study involved patients undergoing edge-to-edge mitral valve repair at a single institution from 1997 to 2003. Preoperative and postoperative echocardiograms were compared. Postoperative morbidity was examined including need for reoperation and long-term medical management. Thirty-day survival and long-term actuarial survival were also determined.

RESULTS: Seventy-one patients comprised this study. Mitral regurgitation on echocardiogram went from 3.43 ± 0.86 to 0.39 ± 0.61 (p < 0.001) following repair. Thirty-day mortality was 3 of 71 (4.2%) patients. Actuarial survivals at 24 and 60 months were 84.5% and 58.3%, respectively; adjusted excluding noncardiac death they were 89.5% and 82.3%, respectively. Forty (56.3%) patients had concomitant ring placement and experienced similar survival to those repaired with the bow-tie stitch alone. Home telephone follow-up was conducted, and current medical therapy was determined on 51 patients; 59% were on a ß-blocker, 31% were on an angiotensin-converting enzyme (ACE) inhibitor, 27% were on a diuretic, and 22% were on digoxin. All were New York Heart Association (NYHA) class I or II. Three patients (4.2%) underwent mitral valve reoperation after a mean of 299 ± 429 days. In no case did the bow-tie suture rupture.

CONCLUSIONS: Edge-to-edge mitral valve repair is a valuable tool in the armamentarium available to treat complex cases of mitral insufficiency or as an adjunct to standard repair techniques that fail to achieve an acceptable result.




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