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Ann Thorac Surg 2004;77:2201-2202
© 2004 The Society of Thoracic Surgeons

Case report

Human papillomavirus and squamous cell carcinoma in a solitary tracheal papilloma

Chung-Wah Lam, MDa, Alan Ronald Talbot, MDb,d, Kun-Tu Yeh, MDc, Sing-Chun Lina, Chia-En Hsieha, Hsin-Yuan Fang, MDa*

a Departments of Surgery, Changhua Christian Hospital, Changhua, Taiwan
b Critical Care Medicine, Changhua Christian Hospital, Changhua, Taiwan
c Pathology, Changhua Christian Hospital, Changhua, Taiwan
d Department of Internal Medicine, Chung Shan Medical University, Taichung, Taiwan

Accepted for publication June 13, 2003.

* Address reprint requests to Dr Fang, Department of Surgery, Changhua Christian Hospital, No. 135 Nanhsiao St, Changhua, 500 Taiwan
e-mail: 51302{at}cch.org.tw

We report the case of a 52-year-old woman suffering from breathlessness on exertion. A chest radiograph identified a lesion in the intrathoracic trachea. A tumor 0.4 x 0.5 x 0.7 cm in size causing an approximately 80% reduction in the cross-sectional area of the trachea 3 cm above the carina was removed, and histology showed moderately differentiated squamous cell carcinoma. Intrathoracic resection of the tumor and anastomosis was performed through a right lateral thoracotomy. The final histology examination showed atypical papilloma. Polymerase chain reaction–restriction fragment length polymorphism confirmed human papillomavirus-6b in the tumor. The patient remained well 18 months after surgical intervention without recurrence.




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[Abstract] [Full Text] [PDF]


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