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Ann Thorac Surg 2004;77:1860-1869
© 2004 The Society of Thoracic Surgeons

Review

Thymic tumors

Frank C. Detterbeck, MDa*, Alden M. Parsons, MDa

a Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA

* Address reprint requests to Dr Detterbeck, Division of Cardiothoracic Surgery, Medical School Wing C, Room 354, CB #7065, University of North Carolina, Chapel Hill, NC 27599-7065, USA
e-mail: fdetter{at}med.unc.edu

Thymic tumors include thymic carcinoma, which exhibit aggressive behavior, and thymomas, which manifest a more indolent course. Complete resection is the mainstay of treatment, and there appears to be little benefit to partial resection. Postoperative radiotherapy may be useful in incompletely resected patients. Preoperative chemotherapy appears to increase the rate of complete resection and survival of patients with a stage III or IVa thymoma and should strongly be considered in such cases.




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