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Right arrow Lung - cancer

Ann Thorac Surg 2004;77:1484-1491
© 2004 The Society of Thoracic Surgeons

Review

Photodynamic therapy in nonsmall cell lung cancer: a systematic review

Donna E. Maziak, MDCMa*, Barbara R. Markman, MAb, Jean A. MacKay, MAb, William K. Evans, MDc Cancer Care Ontario Practice Guidelines Initiative Lung Cancer Disease Site Group*

a University of Ottawa, Ottawa Hospital–General Campus, Ottawa, Canada
b Practice Guidelines Initiative, Cancer Care Ontario Program in Evidence-Based Care, McMaster University–Courthouse T27, Hamilton, Canada
c Cancer Care Ontario, Toronto, Ontario, Canada

* Address reprint requests to Dr Maziak, University of Ottawa, Ottawa Hospital–General Campus, 501 Smyth Rd 6NW-6356, Ottawa, Ontario K1H 8L6, Canada.
e-mail: dmaziak{at}ohri.ca

A systematic review and evaluation of evidence for photodynamic therapy in nonsmall cell lung cancer was undertaken. Two authors selected relevant articles according to predefined criteria. External feedback was obtained from Ontario clinicians and the provincial Lung Cancer Disease Site Group approved the review. The Group concluded that photodynamic therapy may have a role in treating superficial early stage disease or in palliating symptoms in late stage disease. The safety and effectiveness of photodynamic therapy compared with other treatment modalities remains undefined. Serious adverse effects can occur; therefore, the suitability of patients for this treatment should be carefully assessed.




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