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Ertan Sagbas
Belhhan Akpinar
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Ann Thorac Surg 2004;77:619-625
© 2004 The Society of Thoracic Surgeons


Original article: cardiovascular

Does off-pump CABG reduce gastrointestinal complications?

Ilhan Sanisoglu, MDa, Mustafa Guden, MDa, Zehra Bayramoglu, MDa, Ertan Sagbas, MDa, Cengiz Dibekoglu, MDb, S. Yavuz Sanisoglu, PhDc, Belhhan Akpinar, MDa*

a Department of Cardiovascular Surgery, Istanbul, Turkey
b Department of General Surgery, Kadir Has University Medical Faculty, Florence Nightingale Hospital, Istanbul, Turkey
c Department of Biostatistics, Gulhane Military Medical Academy, Etlik, Ankara, Turkey

Accepted for publication August 6, 2003.

* Address reprint requests to Dr Akpinar, Department of Cardiovascular Surgery, Kadir Has University Medical Faculty, Florence Nightingale Hospital, Abide-I Hürriyet Cad. No. 290, Istanbul, Turkey.
e-mail: belh{at}turk.net

BACKGROUND: The aim of this study was to compare gastrointestinal complications and associated risk factors among patients undergoing cardiac surgery using off- and on-pump revascularization techniques.

METHODS: A total of 1146 adult patients who underwent coronary artery surgery during a 6-year period were evaluated retrospectively. Group 1 consisted of 546 patients operated using off-pump techniques and group 2 consisted of 600 cases operated with cardiopulmonary bypass. Patients were compared and evaluated for gastrointestinal complications and possible associated risk factors using univariate and multivariate logistic regression analysis.

RESULTS: Overall mortality was 1.6% in group 1 and 2.2% in group 2 (p = 0.523). Mortality due to gastrointestinal complications was 38.5% and 35.7% respectively in group 1 and group 2. The mean EuroSCORE value was 5.1 ± 2.8 in group 1 and 3.8 ± 2.4 in group 2 (p < 0.001). The most common gastrointestinal complication in the off-pump group was gastrointestinal bleeding. The leading complication in group 2 was intestinal ischemia.

CONCLUSIONS: The incidence rates of gastrointestinal complications were similar in the on- and off-pump coronary artery bypass groups, the type of gastrointestinal complications, however, was different. Mortality rate due to these complications was also similar and remained high, regardless of the type of surgery. Cardiopulmonary bypass did not emerge as a risk factor for gastrointestinal complications, but prolonged cardiopulmonary bypass (longer than 98 minutes) resulted in a high incidence of such complications. Old age and advanced arteriosclerosis emerged as risk factors in both groups resulting in gastrointestinal complications suggesting the ischemic nature of the injury.




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