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William C. Conner
Gregory W. Fink
Karen M. McGinnis
George M. Alfieris
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Ann Thorac Surg 2004;77:334-336
© 2004 The Society of Thoracic Surgeons


Case report

Surgical management of leiomyosarcoma of the mediastinum

William C. Conner, MD*a, Gregory W. Fink, MDa, Karen M. McGinnis, MDa, George M. Alfieris, MDa

a Department of Surgery, State University of New York, Upstate Medical Center, Syracuse, New York, USA

Accepted for publication April 29, 2003.

* Address reprint requests to Dr Shiraishi, Division of Pediatrics, Children's Research Hospital, Kyoto Prefectural University of Medicine, Kyoto, Japan 602-8566.
e-mail: isao{at}koto.kpu-m.ac.jp

Leiomyosarcoma of the mediastinum is sufficiently rare; therefore therapeutic approaches are not well defined. Current therapy primarily rests with the thoracic surgeon. We report a single case of a large leiomyosarcoma of the mediastinum invading the heart and right lung. Our diagnostic and therapeutic approach to this patient is presented and the pertinent literature is reviewed. We conclude that little advancement has been made with regard to adjuvant therapies for leiomyosarcoma of the mediastinum, and the only opportunity for cure remains with full surgical extirpation.




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