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Ann Thorac Surg 2003;76:2094-2097
© 2003 The Society of Thoracic Surgeons

Case report

Use of recombinant factor VIIa as a rescue treatment for intractable bleeding following repeat aortic arch repair

Greg Stratmann, MD, PhDa*, Isobel A. Russell, MD, PhDb, Scott H. Merrick, MDa

a Department of Anesthesia and Perioperative Care, University of California at San Francisco, San Francisco, California, USA
b Department of Surgery, University of California at San Francisco, San Francisco, California, USA

Accepted for publication April 9, 2003.

* Address reprint requests to Dr Stratmann, Department of Anesthesia and Perioperative Care, Mailbox 0464, Room U 368 P, Moffitt Hospital, 513 Parnassus Ave., San Francisco, CA 94143, USA
e-mail: gstratmann{at}anesthesia.ucsf.edu

Hemorrhage, refractory to aggressive conventional therapy, at a rate of 16 L/hr following separation from cardiopulmonary bypass for aortic arch repair, was controlled with a dose of 90 µg/kg of recombinant factor VIIa, repeated once after 2 hours.




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