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Ann Thorac Surg 2003;76:1759-1766
© 2003 The Society of Thoracic Surgeons

Review

Pulmonary arteriovenous malformations after cavopulmonary anastomosis

Brian W. Duncan, MDa*, Shailesh Desai, PhDa

a Pediatric and Congenital Heart Surgery, The Children’s Hospital at The Cleveland Clinic, and The Department of Molecular Cardiology, The Cleveland Clinic Foundation, Cleveland, Ohio, USA

* Address reprint requests to Dr Duncan, Pediatric and Congenital Heart Surgery/M41, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
e-mail: duncanb{at}ccf.org

Pulmonary arteriovenous malformations (PAVMs) are a cause of progressive cyanosis after cavopulmonary anastomosis in children with single ventricle physiology who are on the pathway leading to a Fontan procedure. Investigations into possible mechanisms for the etiology of PAVMs are ongoing and suggest that the liver might play a key regulatory role in the development of these lesions.




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