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Ann Thorac Surg 2003;76:1293-1295
© 2003 The Society of Thoracic Surgeons

Case report

Thrombolytic therapy for delayed, in-hospital stroke after cardiac surgery

Ikuo Fukuda, MD*a, Tomohiro Imazuru, MDb, Motoo Osaka, MDb, Ko Watanabe, MDb, Kotoo Meguro, MDc, Mitsuyosi Wada, MDd

a Department of Surgery I, Hirosaki University School of Medicine, Hirosaki, Aomori, Japan
b Department of Cardiovascular Surgery, Tsukuba Medical Center Hospital, Japan
c Department of Neurosurgery, Tsukuba Medical Center Hospital, Japan
d Department of Radiology, Tsukuba Medical Center Hospital, Tsukuba, Ibaraki, Japan

Accepted for publication February 15, 2003.

* Address reprint requests to Dr Fukuda, Department of Surgery I, Hirosaki University School of Medicine, 5 Zaifu-cho, Hirosaki, Aomori, 036-8562 Japan
e-mail: ikuofuku{at}cc.hirosaki-u.ac.jp

Five patients who had delayed stroke after cardiac surgery underwent intraarterial administration of a fibrinolytic agent for thromboembolism (n = 4) or thrombosis (n = 1) of the cerebral artery. Complete recanalization of the occluded artery was obtained in 3 patients and partial recanalization in 2. Additional angioplasty for basilar artery stenosis was performed in 1 patient. No patients exhibited rebleeding into the pericardial space or wound bleeding. All patients survived with moderate or full functional recovery. Immediate cerebral angiography and local thrombolysis may improve functional outcome and survival in patients with postcardiotomy cerebral thromboembolism.




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A. Aleu, P. Mellado, C. Lichy, M. Kohrmann, and P. D. Schellinger
Hemorrhagic Complications After Off-Label Thrombolysis for Ischemic Stroke
Stroke, February 1, 2007; 38(2): 417 - 422.
[Abstract] [Full Text] [PDF]


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