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Giovanni Troise
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Ann Thorac Surg 2003;76:1107-1113
© 2003 The Society of Thoracic Surgeons


Original article: cardiovascular

Mass regression in aortic stenosis after valve replacement with small size pericardial bioprosthesis

Giordano Tasca, MDa*, Federico Brunelli, MDa, Marco Cirillo, MDa, Andrea Amaducci, MDa, Zen Mhagna, MDa, Giovanni Troise, MDa, Eugenio Quaini, MDa

a Department of Cardiac Surgery, Hospital Poliambulanza, Brescia, Italy

Accepted for publication April 8, 2003.

* Address reprint requests to Dr Tasca, UF di Cardiochirurgia, Casa di Cura, Poliambulanza, Via L. Bissolati 57, 25125 Brescia, Italy
e-mail: cch-segreteria.poli{at}poliambulanza.it

BACKGROUND: The aim of the study was to determine whether left ventricular mass regression is influenced by valve size after the implantation of a Carpentier-Edwards Perimount (CEP) pericardial bioprosthesis for pure aortic stenosis.

METHODS: Patients receiving 19-mm, 21-mm, and 23-mm CEP aortic valves underwent echocardiography preoperatively and at least 1 year after surgery (mean, 2.3 ± 1 years) and the echocardiograms were compared within and between groups.

RESULTS: The study involved a total of 88 patients: 34 receiving 19-mm CEPs, 29 receiving 21-mm CEPs, and 25 receiving 23-mm CEPs. The mean postoperative prosthetic gradients were respectively 20.6 ± 6.6 mm Hg, 17.9 ± 5.8 mm Hg, and 13.2 ± 4.1 mm Hg (p = 0.0001); the mean postoperative valve areas were respectively 1.24 ± 0.16 cm2, 1.45 ± 0.2 cm2, and 1.63 ± 0.21 cm2 (p = 0.0001). In comparison with the preoperative echocardiographic measurements absolute left ventricular mass significantly decreased by -54.1 ± 48.8 g, -54.1 ± 55.1 g, and -74.4 ± 57.4 g respectively with no statistically significant between-group difference (analysis of variance) but ventricular septum and posterior wall thickness significantly decreased in each group (p < 0.05).

CONCLUSIONS: The implantation of 19-mm, 21-mm, and 23-mm CEP aortic prostheses significantly reduces left ventricular mass without any size-related differences.




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