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Ann Thorac Surg 2003;76:287-290
© 2003 The Society of Thoracic Surgeons

Case report

Decreased plasma neurohormones and improved cardiac performance after surgical treatment of chronic pulmonary embolism

Igor I. Tulevski, MDa*, Paul Bresser, PhDb, Alexander Hirsch, BSa, Maarten Groenink, PhDa, Richard N. Channick, MDc, Stuart W. Jamieson, MDd, Barbara J. M. Mulder, PhDa

a Department of Cardiology, Amsterdam The Netherlands
b Department of Pulmonology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
c Divisions of Pulmonary and Critical Care Medicine, San Diego, California, USA
d Division of Cardiothoracic Surgery, University of California San Diego, San Diego, California, USA

Accepted for publication January 8, 2003.

* Address reprint requests to Dr Tulevski, Department of Cardiology, B2-239, Academic Medical Center (AMC), Meibergdreef 9, 1100 DD Amsterdam, The Netherlands
e-mail: i.i.tulevski{at}amc.uva.nl

The findings of this case report suggest that quantitative assessment of plasma neurohormones and magnetic resonance imaging functional parameters in patients with right ventricular pressure overload due to chronic pulmonary embolism might be used as indicators for right ventricular function before and after intervention. Monitoring of changes in these parameters may provide quantitative follow-up of right ventricular function in these patients.






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