ATS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Author home page(s):
Robert W. Emery
Kit V. Arom
William F. Northrup, III
Thomas E. Kersten
Thomas J. Von Rueden
Demetre M. Nicoloff
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Emery, R. W.
Right arrow Articles by Nicoloff, D. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Emery, R. W.
Right arrow Articles by Nicoloff, D. M.

Ann Thorac Surg 2003;75:1815-1819
© 2003 The Society of Thoracic Surgeons

Original article: cardiovascular

Replacement of the aortic valve in patients under 50 years of age: long-term follow-up of the St. Jude medical prosthesis

Robert W. Emery, MDa*, Carla A. Erickson, RNa, Kit V. Arom, MD, PhDa, William F. Northrup, III, MDa, Thomas E. Kersten, MDa, Thomas J. Von Rueden, MDa, Demetre M. Nicoloff, MD, PhDa

a Cardiac Surgical Associates, PA, Minneapolis/St. Paul, Minnesota, USA

* Address reprint requests to Dr Emery, John Nasseff Heart Hospital, 2356 University NEW, STE 258, St. Paul, MN 55407, USA.
e-mail: dremery{at}csa-heart.com

Presented at the Poster Session of the Thirty-eighth Annual Meeting of The Society of Thoracic Surgeons, Fort Lauderdale, FL, Jan 28–30, 2002.

BACKGROUND: Aortic valve replacement in the young adult (aged 18 to 50 years) is a choice between a mechanical prosthesis with attendant lifelong anticoagulation or biological prostheses of varying types that may have limited life expectancy in this age group.

METHODS: The Cardiac Surgical Research Foundation database was accessed to determine long-term outcomes in patients having aortic valve replacement with the St. Jude Medical Valve. This database has been privately maintained since the world’s first St. Jude Medical (SJM) valve implant in 1977. Patients were contacted by questionnaire or by telephone if the survey was not returned. Follow-up was 93% complete.

RESULTS: From October 1977 through October 1997, 271 patients less than 50 years of age had isolated aortic valve replacement. Follow-up was 1957 patient years. Thirty-day operative mortality was 1.1% with 18 late deaths, 4 of which were valve related. Ninety percent of survivor INR responses indicated a frequency of monthly INR checks or less. Valve-related events including percent per patient year and mortality related to these events included thromboembolism, 6 episodes (0.3% per patient year, no deaths); anticoagulant-related bleeding, 6 events (0.3% per patient year, 2 deaths); paravalvular leak, 6 events (0.3% per patient year, 2 deaths); valve thrombosis, 2 events (0.1% per patient year, no deaths); and endocarditis, 3 events (0.15% per patient year, no deaths). There was no incidence of structural valve failure.

CONCLUSIONS: The SJM valve has a long record of excellent performance with durability lasting more than 20 years. The incidence of untoward events is low and death over time due to valve-related complications is low (4 of 271). The SJM valve has become our valve of choice for younger patients.




This article has been cited by other articles:


Home page
 Eur Heart JHome page
L. M.A. Klieverik, J. A. Bekkers, J. W. Roos, M.J.C. Eijkemans, G. B. Raap, Ad. J.J.C. Bogers, and J. J.M. Takkenberg
Autograft or allograft aortic valve replacement in young adult patients with congenital aortic valve disease
Eur. Heart J., June 1, 2008; 29(11): 1446 - 1453.
[Abstract] [Full Text] [PDF]

Home page
 Card Surg AdultHome page
R. W. Emery, A. M. Emery, A. Knutsen, and G. V. Raikar
Aortic Valve Replacement with a Mechanical Cardiac Valve Prosthesis
Card. Surg. Adult, January 1, 2008; 3(2008): 841 - 856.
[Full Text]

Home page
 J Am Coll CardiolHome page
F. Bakhtiary, M. Schiemann, O. Dzemali, S. Dogan, V. Schachinger, H. Ackermann, A. Moritz, and P. Kleine
Impact of Patient-Prosthesis Mismatch and Aortic Valve Design on Coronary Flow Reserve After Aortic Valve Replacement
J. Am. Coll. Cardiol., February 20, 2007; 49(7): 790 - 796.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
F. Bakhtiary, O. Dzemali, T. Wittlinger, A. Moritz, and P. Kleine
Reply to the editor.
J. Thorac. Cardiovasc. Surg., September 1, 2006; 132(3): 727 - 728.
[Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
R. O. Bonow, B. A. Carabello, K. Chatterjee, A. C. de Leon Jr, D. P. Faxon, M. D. Freed, W. H. Gaasch, B. W. Lytle, R. A. Nishimura, P. T. O'Gara, et al.
ACC/AHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 1998 Guidelines for the Management of Patients With Valvular Heart Disease) Developed in Collaboration With the Society of Cardiovascular Anesthesiologists Endorsed by the Society for Cardiovascular Angiography and Interventions and the Society of Thoracic Surgeons
J. Am. Coll. Cardiol., August 1, 2006; 48(3): e1 - e148.
[Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
R. O. Bonow, B. A. Carabello, K. Chatterjee, A. C. de Leon Jr, D. P. Faxon, M. D. Freed, W. H. Gaasch, B. W. Lytle, R. A. Nishimura, P. T. O'Gara, et al.
ACC/AHA 2006 Practice Guidelines for the Management of Patients With Valvular Heart Disease: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 1998 Guidelines for the Management of Patients With Valvular Heart Disease) Developed in Collaboration With the Society of Cardiovascular Anesthesiologists Endorsed by the Society for Cardiovascular Angiography and Interventions and the Society of Thoracic Surgeons
J. Am. Coll. Cardiol., August 1, 2006; 48(3): 598 - 675.
[Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
F. Bakhtiary, M. Schiemann, O. Dzemali, T. Wittlinger, M. Doss, H. Ackermann, A. Moritz, and P. Kleine
Stentless bioprostheses improve postoperative coronary flow more than stented prostheses after valve replacement for aortic stenosis
J. Thorac. Cardiovasc. Surg., April 1, 2006; 131(4): 883 - 888.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
R. W. Emery and A. M. Emery
Reply
Ann. Thorac. Surg., February 1, 2006; 81(2): 788 - 788.
[Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
G. B. Luciani, A. Favaro, G. Casali, F. Santini, and A. Mazzucco
Ross Operation in the Young: A Ten-Year Experience
Ann. Thorac. Surg., December 1, 2005; 80(6): 2271 - 2277.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
R. W. Emery, C. C. Krogh, K. V. Arom, A. M. Emery, K. Benyo-Albrecht, L. D. Joyce, and D. M. Nicoloff
The St. Jude Medical Cardiac Valve Prosthesis: A 25-Year Experience With Single Valve Replacement
Ann. Thorac. Surg., March 1, 2005; 79(3): 776 - 782.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
M. Ruel, A. Kulik, B. K. Lam, F. D. Rubens, P. J. Hendry, R. G. Masters, P. Bedard, and T. G. Mesana
Long-term outcomes of valve replacement with modern prostheses in young adults
Eur. J. Cardiothorac. Surg., March 1, 2005; 27(3): 425 - 433.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
J. A. Carr and E. B. Savage
Aortic valve repair for aortic insufficiency in adults: a contemporary review and comparison with replacement techniques
Eur. J. Cardiothorac. Surg., January 1, 2004; 25(1): 6 - 15.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 2003 by The Society of Thoracic Surgeons.