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Ann Thorac Surg 2003;75:1005-1007
© 2003 The Society of Thoracic Surgeons

Case report

Mechanical ventricular support lowers pulmonary vascular resistance in a patient with congential heart disease

Jason A. Petrofski, MDa, Charles W. Hoopes, MD, PhDa, Thomas M. Bashore, MDb, Stuart D. Russell, MDb, Carmelo A. Milano, MDa*

a Division of Cardiothoracic Surgery, Department of Surgery, Durham, NC, USA
b Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA

Accepted for publication August 27, 2002.

* Address reprint requests to Dr Milano, Box 3043, Department of Surgery, Duke University Medical Center, Durham, NC 27703, USA
e-mail: milan002{at}mc.duke.edu

Severely elevated pulmonary vascular resistance (PVR) is a relative contraindication to orthotopic heart transplantation. A potential novel strategy to reverse elevated PVR may be implantation of a chronic left ventricular assist device with subsequent left ventricular unloading. We present a patient with elevated PVR secondary to congenital heart disease who was listed for heart-lung transplant. The patient underwent placement of biventricular assist devices and subsequently experienced marked reduction of PVR, ultimately enabling successful heart transplantation.




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