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Ann Thorac Surg 2003;75:568-569
© 2003 The Society of Thoracic Surgeons

Case report

Mediastinal talcoma masquerading as thymoma

Zahoor Ahmed, MDa, Joseph B. Shrager, MDa*

a Section of General Thoracic Surgery, Division of Cardio-thoracic Surgery, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA

Accepted for publication August 22, 2002.

* Address reprint requests to Dr Shrager, General Thoracic Surgery, Hospital of the University of Pennsylvania, 4 Silverstein, 3400 Spruce St, Philadelphia, PA 19104, USA.
e-mail: jshrag{at}mail.med.upenn.edu

We report a young woman with a large, calcified anterior mediastinal mass discovered 18 months following a left talc pleurodesis. The lesion was evaluated and treated as the thymoma or teratoma that it appeared to be, with excision by a transcervical approach. Pathologic examination revealed a giant talc granuloma. Awareness of such a possibility following talc pleurodesis may allow surgeons to avoid unnecessary mediastinal exploration, and its occurrence suggests that talc administration simultaneous with mechanical pleurodesis should be avoided.




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