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Ann Thorac Surg 2003;75:514-519
© 2003 The Society of Thoracic Surgeons

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Original article: cardiovascular

Surgery for acute type A dissection using antegrade selective cerebral perfusion: experience with 122 patients

^a Department of Cardiopulmonary Surgery, St. Antonius Hospital, Nieuwegein, The Netherlands
^b Department of Cardiac Surgery, Policlinico Sant’Orsola, University of Bologna, Bologna, Italy

Accepted for publication August 21, 2002.

* Address reprint requests to Dr Di Eusanio, Department of Cardiopulmonary Surgery, St. Antonius Hospital, Koekoekslaan 1, 3435 CM Nieuwegein, The Netherlands
e-mail: m_dieus{at}hotmail.com

BACKGROUND: Antegrade selective cerebral perfusion (ASCP) has proved to be a reliable method of brain protection during surgery of the thoracic aorta, but its use during aortic dissection surgery still remains controversial. In this study, we present our results after the operative repair of acute type A aortic dissections using ASCP and moderate hypothermic circulatory arrest.

METHODS: Between October 1995 and August 2001, 122 patients (76 men, 46 women) underwent repair of acute type A aortic dissection with the aid of ASCP and open distal anastomosis. The average age of the patients was 61 ± 12 (mean ± standard deviation). Preoperative complications included cardiac tamponade (n = 34; 27.0%), aortic regurgitation (n = 27; 22.1%), and new neurological deficits (n = 11; 9%).

RESULTS: Stepwise logistic regression revealed preoperative cardiac tamponade (p = 0.018) and new neurological deficits (p = 0.017) to be independent determinants for hospital mortality (19.7%). Permanent neurological complications occurred in 7% of the patients. Independent risk factors for temporary neurological dysfunction (11.2%) included cardiac tamponade (p = 0.019) and preoperative neurological deficits (p = 0.000).

CONCLUSIONS: In our experience, the surgical treatment of acute type A aortic dissection with the aid of ASCP was associated with acceptable hospital mortality and neurologic morbidity rates.

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