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Ann Thorac Surg 2002;74:2182-2183
© 2002 The Society of Thoracic Surgeons

Case report

Activated recombinant factor VII for control of diffuse bleeding after implantation of ventricular assist device

Evgenij V. Potapov, MDa*, Miralem Pasic, MD, PhDa, Matthias Bauer, MDa, Roland Hetzer, MD, PhDa

a Deutsches Herzzentrum Berlin, Berlin, Germany

Accepted for publication July 1, 2002.

* Address reprint requests to Dr Potapov, Deutsches Herzzentrum Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.
e-mail: potapov{at}dhzb.de

Patients with prolonged severe cardiogenic shock requiring implantation of a biventricular assist device may develop diffuse bleeding due to alteration of hepatic and renal function and subsequent coagulopathy. Bleeding control in these patients may be difficult despite massive use of blood products. We report on the successful use of recombinant activated factor VII for control of massive bleeding after implantation of a biventricular assist device in a patient with prolonged severe cardiogenic shock.




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