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Ann Thorac Surg 2002;74:1625-1630
© 2002 The Society of Thoracic Surgeons


Original article: cardiovascular

Anomalous origin of the left coronary artery from the pulmonary artery: results of surgical correction in five infants

Ragini Pandey, FRCS (Ed)a, Giovanna Ciotti, MDa, Marco Pozzi, MDa*

a Cardiac Unit, Royal Liverpool Children’s Hospital, Alder Hey, Liverpool, United Kingdom

Accepted for publication May 29, 2002.

* Address reprint requests to Dr Pozzi, Cardiac Unit, Royal Liverpool Children’s Hospital, Alder Hey, Eaton Rd, Liverpool L12 2AP, UK.
e-mail: mpozzi75{at}hotmail.com

BACKGROUND: Five infants operated on for anomalous origin of the left coronary artery from the pulmonary artery were retrospectively analyzed. The mean age at operation was 12 ± 6.7 weeks (95% confidence interval, 3.5 to 20 weeks), and mean weight at operation was 4.43 ± 0.68 kg (95% confidence interval, 3.7 to 5.27 kg). All babies presented in infancy with left ventricular failure. Three had evidence of ischemia with left ventricular strain, and two had Q waves in anterolateral leads on electrocardiograph. Cross-sectional echocardiography showed dilated left ventricles with poor contractility in all babies with fractional shortening of 15.8% ± 4.02% (95% confidence interval, 12% to 20%); moderate mitral regurgitation was seen in all babies.

METHODS: All babies underwent operation as soon as the diagnosis was made. Four babies had direct reimplantation of left coronary artery into the aorta, and 1 had tunnel repair. Intraaortic balloon counterpulsation was used in 1 baby for hemodynamic instability and as prophylaxis in the remaining 4 babies postoperatively for 115 ± 26.2 hours (95% confidence interval, 72 to 144 hours).

RESULTS: All babies had delayed closure of the chest. There was no operative mortality. One baby was reoperated on for tunnel stenosis as well as pulmonary stenosis 4 months after primary repair. All babies were followed for 192 patient-months and show an improved fractional shortening.

CONCLUSIONS: Early operation, early institution of intraaortic balloon counter pulsation for left ventricular support, and delayed sternal closure are the key to good results.




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J. Thorac. Cardiovasc. Surg.Home page
G. Kalavrouziotis, A. Karunaratne, S. Raja, G. Ciotti, M. Purohit, A. F. Corno, and M. Pozzi
Intra-aortic balloon pumping in children undergoing cardiac surgery: An update of the Liverpool experience
J. Thorac. Cardiovasc. Surg., June 1, 2006; 131(6): 1382 - 1389.
[Abstract] [Full Text] [PDF]




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