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Ann Thorac Surg 2002;74:S1413-S1415
© 2002 The Society of Thoracic Surgeons


Supplement: Cardiothoracic Techniques and Technologies

Obliteration of femoral artery pseudoaneurysm by thrombin injection

James R. Edgerton, MDa*, David O. Moore, MDa, Donna Nichols, RVTa, B.Ward Lane, MDa, Mitchell J. Magee, MDa, Todd M. Dewey, MDa, Michael J. Mack, MDa

a Cardiopulmonary Research Science and Technology Institute (CRSTI), Dallas, Texas, USA

* Address reprint requests to Dr Edgerton, 7777 Forest Lane, Suite A323, Dallas TX 75230, USA.
e-mail: edgertonjr{at}aol.com

Presented at the Eighth Annual Cardiothoracic Techniques and Technologies Meeting 2002, Miami Beach, FL, Jan 23–26, 2002.

BACKGROUND: Femoral artery pseudyoaneurysms are a common complication after femoral access for transcatheter procedures, frequently requiring operative repair. We review the safety and efficacy of a novel nonsurgical method of pseudoaneurysm treatment.

METHODS: From June 1998 to November 2001, a total of 47 femoral artery pseudoaneurysms in 46 patients were treated by bedside ultrasound-guided injection of dilute topical thrombin. All pseudoaneurysms occurred after femoral access for transcatheter procedures, and were diagnosed clinically and confirmed with ultrasound imaging. Clinical follow-up was performed and included ultrasound (2 hours to 1 month) in 64.4% of patients, including any patient with a symptomatic or clinical change.

RESULTS: Pseudoaneurysms ranged in size from 1.5 to 4.5 cm. Of 47 pseudoaneurysms, 45 were successfully obliterated on the initial injection. After successful obliteration of pseudoaneurysm, 1 patient sustained thrombosis of the tibioperoneal trunk that required surgical embolectomy, yielding a complication rate of 2%. Four pseudoaneurysms recurred after initially successful obliteration. In 1 of these cases, the patient was taken directly to surgery, and 3 were successfully treated with repeat injection, for an overall success rate of 93.6%.

CONCLUSIONS: Obliteration of femoral artery pseudoaneurysm by injection is safe and effective, and may be associated with decreased morbidity. Recurrent pseudoaneurysms may be safely reinjected, with a high success rate.




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