|
|
||||||||
Ann Thorac Surg 2002;74:712-719
© 2002 The Society of Thoracic Surgeons
a Department of Cardiothoracic Anesthesia, Linköping Heart Center, University Hospital, Linköping, Sweden
b Department of Cardiothoracic Surgery, Linköping Heart Center, University Hospital, Linköping, Sweden
Accepted for publication April 25, 2002.
* Address reprint requests to Dr Svedjeholm, Department of Cardiothoracic Surgery, Linköping Heart Center, University Hospital, S-581 85 Linköping, Sweden
e-mail: rolf.svedjeholm{at}lio.se
Background. An increasing proportion of patients undergoing coronary artery bypass grafting (CABG) are diabetics. Patient characteristics, early postoperative outcome, and midterm survival in diabetic patients after CABG were investigated.
Methods. A total of 2779 consecutive patients undergoing isolated CABG during 1995 to 1999 were studied, 19.4% of whom had diabetes mellitus. Demographic and peri-procedural data were registered prospectively in a computerized institutional database.
Results. The diabetic group was younger and included a higher proportion of women, and patients with hypertension, triple-vessel disease, and unstable angina. They required a higher number of bypasses, and longer cross-clamp and cardiopulmonary bypass times. Intensive care unit and hospital stays were prolonged and the need for inotropic agents, hemotransfusions, and dialysis was higher in the diabetic group. Renal failure, stroke (4.3% versus 1.7%), mediastinitis, and wound infections were more frequently encountered. Thirty-day mortality was 2.6% versus 1.6% (p = 0.15). Cumulative 5-year survival was 84.4% versus 91.3% (p < 0.001).
Conclusions. Short-term mortality was acceptable in diabetic patients after CABG but they had increased postoperative morbidity in comparison with nondiabetic patients, particularly with regard to renal function, cerebral complications, and infections. Midterm survival was impaired in diabetic patients mainly because of a less favorable outcome in patients treated with insulin.
This article has been cited by other articles:
![]() |
H. L. Lazar, M. McDonnell, S. R. Chipkin, A. P. Furnary, R. M. Engelman, A. R. Sadhu, C. R. Bridges, C. K. Haan, R. Svedjeholm, H. Taegtmeyer, et al. The society of thoracic surgeons practice guideline series: blood glucose management during adult cardiac surgery. Ann. Thorac. Surg., February 1, 2009; 87(2): 663 - 669. [Full Text] [PDF] |
||||
![]() |
B. Marcheix, F. Vanden Eynden, P. Demers, D. Bouchard, and R. Cartier Influence of Diabetes Mellitus on Long-Term Survival in Systematic Off-Pump Coronary Artery Bypass Surgery Ann. Thorac. Surg., October 1, 2008; 86(4): 1181 - 1188. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. E. Halkos, J. D. Puskas, O. M. Lattouf, P. Kilgo, F. Kerendi, H. K. Song, R. A. Guyton, and V. H. Thourani Elevated preoperative hemoglobin A1c level is predictive of adverse events after coronary artery bypass surgery J. Thorac. Cardiovasc. Surg., September 1, 2008; 136(3): 631 - 640. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. E. Antunes, J. F. de Oliveira, and M. J. Antunes Coronary surgery in patients with diabetes mellitus: a risk-adjusted study on early outcome. Eur. J. Cardiothorac. Surg., August 1, 2008; 34(2): 370 - 375. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. Ascione, C.A. Rogers, C. Rajakaruna, and G.D. Angelini Inadequate Blood Glucose Control Is Associated With In-Hospital Mortality and Morbidity in Diabetic and Nondiabetic Patients Undergoing Cardiac Surgery Circulation, July 8, 2008; 118(2): 113 - 123. [Abstract] [Full Text] [PDF] |
||||
![]() |
F. Filsoufi, P. B. Rahmanian, J. G. Castillo, J. I. Mechanick, S. K. Sharma, and D. H. Adams Diabetes is not a risk factor for hospital mortality following contemporary coronary artery bypass grafting Interactive CardioVascular and Thoracic Surgery, December 1, 2007; 6(6): 753 - 758. [Abstract] [Full Text] [PDF] |
||||
![]() |
B. P. Choudhary, C. Antoniades, A. F. Brading, A. Galione, K. Channon, and D. P. Taggart Diabetes Mellitus as a Predictor for Radial Artery Vasoreactivity in Patients Undergoing Coronary Artery Bypass Grafting J. Am. Coll. Cardiol., September 11, 2007; 50(11): 1047 - 1053. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. Rajakaruna, C. A. Rogers, C. Suranimala, G. D. Angelini, and R. Ascione The effect of diabetes mellitus on patients undergoing coronary surgery: A risk-adjusted analysis J. Thorac. Cardiovasc. Surg., October 1, 2006; 132(4): 802 - 810. [Abstract] [Full Text] [PDF] |
||||
![]() |
D. E Birnbaum and K. Lehle CPB in High-Risk Groups: CPB in Diabetics Perfusion, July 1, 2006; 21(4): 235 - 238. [PDF] |
||||
![]() |
I. K. Toumpoulis, C. E. Anagnostopoulos, S. Balaram, D. G. Swistel, R. C. Ashton Jr, and J. J. DeRose Jr Does Bilateral Internal Thoracic Artery Grafting Increase Long-Term Survival of Diabetic Patients? Ann. Thorac. Surg., February 1, 2006; 81(2): 599 - 607. [Abstract] [Full Text] [PDF] |
||||
![]() |
J.-S. Choi, K. R. Cho, and K.-B. Kim Does Diabetes Affect the Postoperative Outcomes After Total Arterial Off-Pump Coronary Bypass Surgery in Multivessel Disease? Ann. Thorac. Surg., October 1, 2005; 80(4): 1353 - 1360. [Abstract] [Full Text] [PDF] |
||||
![]() |
F. H. Edwards, V. A. Ferraris, D. M. Shahian, E. Peterson, A. P. Furnary, C. K. Haan, and C. R. Bridges Gender-Specific Practice Guidelines for Coronary Artery Bypass Surgery: Perioperative Management Ann. Thorac. Surg., June 1, 2005; 79(6): 2189 - 2194. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. Kubal, A. K. Srinivasan, A. D. Grayson, B. M. Fabri, and J. A.C. Chalmers Effect of Risk-Adjusted Diabetes on Mortality and Morbidity After Coronary Artery Bypass Surgery Ann. Thorac. Surg., May 1, 2005; 79(5): 1570 - 1576. [Abstract] [Full Text] [PDF] |
||||
![]() |
O. Friberg, R. Svedjeholm, B. Soderquist, H. Granfeldt, T. Vikerfors, and J. Kallman Local Gentamicin Reduces Sternal Wound Infections After Cardiac Surgery: A Randomized Controlled Trial Ann. Thorac. Surg., January 1, 2005; 79(1): 153 - 161. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. L. Thompson, K. C. Dunn, M. C. Menon, L. E. Kearns, and S. S. Braithwaite Hyperglycemia in the Hospital Diabetes Spectr, January 1, 2005; 18(1): 20 - 27. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. E. Woods, J. M. Smith, S. Sohail, A. Sarah, and A. Engle The Influence of Type 2 Diabetes Mellitus in Patients Undergoing Coronary Artery Bypass Graft Surgery: An 8-Year Prospective Cohort Study Chest, December 1, 2004; 126(6): 1789 - 1795. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. K. Srinivasan, A. D. Grayson, and B. M. Fabri On-Pump Versus Off-Pump Coronary Artery Bypass Grafting in Diabetic Patients: A Propensity Score Analysis Ann. Thorac. Surg., November 1, 2004; 78(5): 1604 - 1609. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. J. Mack, P. Brown, F. Houser, M. Katz, A. Kugelmass, A. Simon, S. Battaglia, L. Tarkington, S. Culler, and E. Becker On-Pump Versus Off-Pump Coronary Artery Bypass Surgery in a Matched Sample of Women: A Comparison of Outcomes Circulation, September 14, 2004; 110(11_suppl_1): II-1 - II-6. [Abstract] [Full Text] [PDF] |
||||
![]() |
B. J. Leavitt, L. Sheppard, C. Maloney, R. A. Clough, J. H. Braxton, D. C. Charlesworth, R. M. Weintraub, F. Hernandez, E. M. Olmstead, W. C. Nugent, et al. Effect of Diabetes and Associated Conditions on Long-Term Survival After Coronary Artery Bypass Graft Surgery Circulation, September 14, 2004; 110(11_suppl_1): II-41 - II-44. [Abstract] [Full Text] [PDF] |
||||
![]() |
O. Lev-Ran, R. Braunstein, N. Nesher, Y. Ben-Gal, G. Bolotin, and G. Uretzky Bilateral versus single internal thoracic artery grafting in oral-treated diabetic subsets: comparative seven-year outcome analysis Ann. Thorac. Surg., June 1, 2004; 77(6): 2039 - 2045. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. A. Morgan, R. John, A. D. Weinberg, N. J. Colletti, D. M. Mancini, and N. M. Edwards Heart transplantation in diabetic recipients: A decade review of 161 patients at Columbia Presbyterian J. Thorac. Cardiovasc. Surg., May 1, 2004; 127(5): 1486 - 1492. [Abstract] [Full Text] [PDF] |
||||
![]() |
O. Lev-Ran, R. Mohr, D. Pevni, N. Nesher, Y. Weissman, D. Loberman, and G. Uretzky Bilateral internal thoracic artery grafting in diabetic patients: Short-term and long-term results of a 515-patient series J. Thorac. Cardiovasc. Surg., April 1, 2004; 127(4): 1145 - 1150. [Abstract] [Full Text] [PDF] |
||||
![]() |
N. Winer and J. R. Sowers Epidemiology of Diabetes J. Clin. Pharmacol., April 1, 2004; 44(4): 397 - 405. [Abstract] [Full Text] [PDF] |
||||
![]() |
H. L. Lazar, S. R. Chipkin, C. A. Fitzgerald, Y. Bao, H. Cabral, and C. S. Apstein Tight Glycemic Control in Diabetic Coronary Artery Bypass Graft Patients Improves Perioperative Outcomes and Decreases Recurrent Ischemic Events Circulation, March 30, 2004; 109(12): 1497 - 1502. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. Clement, S. S. Braithwaite, M. F. Magee, A. Ahmann, E. P. Smith, R. G. Schafer, and I. B. Hirsch Management of Diabetes and Hyperglycemia in Hospitals Diabetes Care, February 1, 2004; 27(2): 553 - 591. [Full Text] [PDF] |
||||
![]() |
N. K. Wenger Is what's good for the gander good for the goose? J. Thorac. Cardiovasc. Surg., October 1, 2003; 126(4): 929 - 931. [Full Text] [PDF] |
||||
![]() |
D Smith The CARDia trial protocol Heart, October 1, 2003; 89(10): 1125 - 1126. [Full Text] [PDF] |
||||
![]() |
Z. Szabo A simple method to pass a pulmonary artery flotation catheter rapidly into the pulmonary artery in anaesthetized patients Br. J. Anaesth., June 1, 2003; 90(6): 794 - 796. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. S. Hochman and J. E. Tamis-Holland Acute Coronary Syndromes: Does Sex Matter? JAMA, December 25, 2002; 288(24): 3161 - 3164. [Full Text] [PDF] |
||||
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| ANN THORAC SURG | ASIAN CARDIOVASC THORAC ANN | EUR J CARDIOTHORAC SURG |
| J THORAC CARDIOVASC SURG | ICVTS | ALL CTSNet JOURNALS |