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Ann Thorac Surg 2002;74:338-341
© 2002 The Society of Thoracic Surgeons

Original article: general thoracic

Intraoperative intercostal nerve blockade for postthoracotomy pain

Shinzo Takamori, MD*a, Shogo Yoshida, MDa, Akihiro Hayashi, MDa, Toshihiro Matsuo, MDa, Masahiro Mitsuoka, MDa, Kazuo Shirouzu, MDa

a Department of Surgery, Kurume University School of Medicine, Kurume, Japan

Accepted for publication April 21, 2002.

* Address reprint requests to Dr Takamori, Department of Surgery, Kurume University School of Medicine, 67 Asahi-machi, Kurume 830-0011, Japan
e-mail: stakam{at}med.kurume-u.ac.jp

Background. Epidural analgesia is widely employed as a means to control postthoracotomy pain, but is sometimes inadequate. The purpose of this study is to evaluate the effectiveness of intraoperative, temporary, intercostal nerve blockade in addition to epidural analgesia for control of postthoracotomy pain.

Methods. Forty patients undergoing elective lobectomy through antero-axillary thoracotomy were randomized to receive epidural analgesia only (group A, n = 20) or epidural analgesia plus temporary, intraoperative intercostal nerve blockade using 0.25% bupivacaine (group B, n = 20). Postoperative pain was assessed using a subjective analogue visual scale, and with the Prince Henry pain scale. Food intake and nonsteroidal analgesic consumption were also investigated. Serum ACTH and cortisol in each group were measured before and after the operation.

Results. The analogue visual scale scores were significantly higher in group A than group B (p < 0.001), and were significantly higher on the day of operation and postoperative days 1, 2, and 3 (p < 0.001, p < 0.005, p < 0.005, p < 0.05, respectively). Prince Henry pain scale scores were significantly higher on the day of operation and postoperative day 1 (p < 0.05, p < 0.005, respectively). Food intake was significantly lower in group A than in group B (p < 0.05), and nonsteroidal analgesic consumption was not significantly different between groups. There was no significant difference between group A and group B in serum ACTH or in cortisol levels.

Conclusions. Additional intraoperative intercostal nerve blockade provides an additive benefit for postthoracotomy pain relief, especially early after operation.




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