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Ann Thorac Surg 2002;73:1830-1836
© 2002 The Society of Thoracic Surgeons

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Original article: cardiovascular

Preliminary experience with the St. Jude Medical Regent mechanical heart valve in the aortic position: early in vivo hemodynamic results

^a Department of Cardiovascular Sciences, General Hospital "S. Maria Della Misericordia," Udine, Italy

Accepted for publication December 10, 2001.

* Address reprint requests to Dr Gelsomino, U. O. Cardiotoracica, Azienda Ospedaliera S. Maria Della Misericordia, Piazzale S. Maria Della Misericordia 11, 33100 Udine, Italy
e-mail: sandrogelsomino{at}virgilio.it

Background. The St. Jude Medical Regent is a new generation mechanical aortic valve.

Methods. Between March 2000 and July 2001, this valve was implanted in the aortic position in 40 patients (21 men; mean age 59.1 ± 9.0 years). Preoperatively, 24 patients (60%) were in New York Heart Association functional class III or IV. Eighteen patients (45%) underwent associated procedures. Mean valve size was 21.4 ± 2.4 mm. The mean duration of follow-up was 8.5 ± 4.5 months (range, 1 to 16 months).

Results. There were no operative deaths. Early complications included one reoperation for bleeding and one transient low output syndrome. Valve replacement was followed by a significant reduction in mean and peak transaortic gradients over time (p < 0.001) and analysis of variance failed to demonstrate statistical differences between valve size over time (p = not significant). A significant reduction in left ventricular hypertrophy occurred over time (p = 0.01) in all valve sizes (p = not significant between groups): baseline left ventricular mass index was 194 g/cm²; it reduced by 22 g/cm² (p = 0.006) at discharge. Left ventricular mass index decreased from 172 ± 55 g/cm² to 156 ± 44 g/cm² (p = 0.03) from discharge to 2 months. Further reductions were not significant. Relative wall thickness decreased from 0.57 ± 0.13 preoperatively to 0.42 ± 0.06 at discharge (p = 0.001), and again at 2 months (-0.2; p = not significant), and at 1 year (-0.02; p = not significant).

Conclusions. The early experience with the St. Jude Medical Regent valve has been satisfactory.

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Ann. Thorac. Surg. 2002 73: 1836. [Extract] [Full Text] [PDF]

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