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Ann Thorac Surg 2002;73:1292-1294
© 2002 The Society of Thoracic Surgeons

Case report

Flow cytometric analysis of a localized malignant mesothelioma

José Javier Gómez-Román, MD, PhD*a, Roberto Mons-Lera, MD, PhDb, Isabel Seco Olmedo, MDc, José Fernando Val-Bernal, MD, PhDa

a Department of Anatomical Pathology, University Hospital, "Marqués de Valdecilla," National Health Institute, Medical Faculty, Cantabria University, Santander, Spain
b Thoracic Surgery Service, University Hospital, "Marqués de Valdecilla," National Health Institute, Medical Faculty, Cantabria University, Santander, Spain
c General Surgery Service, University Hospital, "Marqués de Valdecilla," National Health Institute, Medical Faculty, Cantabria University, Santander, Spain

Accepted for publication August 17, 2001.

* Address reprint requests to Dr Gómez-Román, Departamento de Anatomía Patológica, Hospital Universitario "Marqués de Valdecilla," Avda de Valdecilla s/n, 39008 Santander (Cantabria), Spain
e-mail: apagrj{at}humv.es

Malignant mesothelioma usually presents as a diffuse neoplasm. We report a localized malignant mesothelioma in the parietal pleura of a patient who was not exposed to asbestos. A complete clinical, pathologic, and immunohistochemical description is provided. Flow cytometric analysis showed an aneuploid DNA content in neoplastic cells. The patient is alive and well 8 months after complete surgical resection. Localized malignant mesothelioma must be included in the differential diagnosis in chest wall-based neoplasms.




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