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Ann Thorac Surg 2001;72:1739-1740
© 2001 The Society of Thoracic Surgeons

Case report

Sarcoma associated with silver coated mechanical heart valve prosthesis

Herko Grubitzsch, MD*a, Hans-Georg Wollert, MDa, Lothar Eckel, MDa

a Heart and Diabetes Centre Mecklenburg-Vorpommern, Clinic of Cardiothoracic and Vascular Surgery, Karlsburg, Germany

Accepted for publication December 28, 2000.

* Address reprint requests to Dr Grubitzsch, Herz- und Diabeteszentrum Mecklenburg-Vorpommern, Klinikum Karlsburg, Klinik für Herz-, Thorax- und Gefässchirurgie, Greifswalder Str 11 A, D-17495 Karlsburg, Germany
e-mail: grubitzsch{at}t-online.de

Sarcomas can develop in association with foreign material (eg, from Dacron vascular prostheses). We report on a left atrial rhabdomyosarcoma that developed within 1 year of mitral valve replacement by a Silzone-coated St. Jude Medical mechanical heart valve. Tumor resection and redo valve replacement were done. Six months later the patient was alive, but an echocardiogram showed tumor recurrence. Although this is a single case, an association between heart valve prostheses and malignant tumors should be considered.




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A Ionescu, N Payne, A G Fraser, J Giddings, G L Grunkemeier, and E G Butchart
Incidence of embolism and paravalvar leak after St Jude Silzone valve implantation: experience from the Cardiff Embolic Risk Factor Study
Heart, September 1, 2003; 89(9): 1055 - 1061.
[Abstract] [Full Text] [PDF]


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