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Ann Thorac Surg 2001;72:1698-1704
© 2001 The Society of Thoracic Surgeons

Original article: general thoracic

Combined video-assisted mediastinoscopy and video-assisted thoracoscopy in the management of lung cancer

Jérôme Mouroux, MD*a, Nicolas Venissac, MDa, Marco Alifano, MDa

a Service de Chirurgie Thoracique, CHU de Nice, Hôpital Pasteur, Nice, France

Accepted for publication June 27, 2001.

* Address reprint requests to Dr Mouroux, Service de Chirurgie Thoracique, Hôpital Pasteur, 30, Avenue de la Voie Romaine - BP 69, 06002 Nice Cedex 1, France
e-mail: chir-thoracique{at}chu-nice.fr

Background. This study seeks to assess the safety and usefulness of combined video-assisted mediastinoscopy and video-assisted thoracoscopy in the management of patients with lung cancer.

Methods. Ten consecutive patients with lung neoplasms were evaluated. Indications for this combined approach included inconclusive findings from imaging techniques concerning locoregional extension and resectability; possible involvement of different structures not accessible to a single procedure; and failure to obtain histologic diagnosis by a single technique.

Results. Histologic diagnosis was obtained in 6 patients without preoperative histologic typing. In 3 patients, in contrast with preoperative imaging studies, combined thoracoscopy and mediastinoscopy showed the resectability of the primary tumor and the absence of metastatic mediastinal lymph nodes. These findings were confirmed at thoracotomy. In 3 other patients prevascular lymph nodes metastases were found. They underwent neoadjuvant chemotherapy; at subsequent operation, a complete resection was possible. In the remaining four cases combined exploration proved definitive contraindications for operation (recognition of oat-cell carcinoma, n = 2; T4 status, n = 1; T3N2, n = 1).

Conclusions. Combined video-assisted mediastinoscopy and video-assisted thoracoscopy seems to be a safe and useful tool in the management of selected patients with lung neoplasms. Both the extent of primary tumor and the possible intrathoracic spread may be exhaustively evaluated. In patients with left lung cancer a complete exploration of the aortopulmonary window is possible.




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