ATS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
 QUICK SEARCH:   [advanced]


     


This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Author home page(s):
Jorge D. Salazar
John R. Doty
William A. Baumgartner
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Salazar, J. D.
Right arrow Articles by Baumgartner, W. A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Salazar, J. D.
Right arrow Articles by Baumgartner, W. A.
Related Collections
Right arrow Extracorporeal circulation
Right arrowRelated Article

Ann Thorac Surg 2001;72:1195-1201
© 2001 The Society of Thoracic Surgeons


Original article: cardiovascular

Stroke after cardiac surgery: short- and long-term outcomes

Jorge D. Salazar, MDa, Robert J. Wityk, MDb, Maura A. Grega, MSNa, Louis M. Borowicz, MSb, John R. Doty, MDa, Jason A. Petrofski, MDa, William A. Baumgartner, MDa

a Division of Cardiac Surgery, The Johns Hopkins University, Baltimore, Maryland, USA
b Department of Neurology, The Johns Hopkins University, Baltimore, Maryland, USA

Accepted for publication May 29, 2001.

Address reprint requests to Dr Baumgartner, Blalock 618-Cardiac Surgery, Johns Hopkins Hospital, 600 N. Wolfe St, Baltimore, MD 21287-4618
e-mail: wbaumgar{at}csurg.jhmi.jhu.edu

Background. Stroke remains a devastating complication of cardiac surgery, but stroke prevention remains elusive. Evaluation of early and long-term clinical outcomes and brain-imaging findings may provide insight into stroke prognosis, etiology, and prevention.

Methods. Five thousand nine hundred seventy-one cardiac surgery patients were prospectively studied for clinical evidence of stroke. Stroke and nonstroke patients were compared by early outcomes. Data collected for stroke patients included brain imaging results, long-term functional status, and survival. Outcome predictors were then determined.

Results. Stroke was diagnosed in 214 (3.6%) patients. Brain imaging demonstrated acute infarction in 72%; embolic in 83%, and watershed in 24%. Survival for stroke patients was 67% at 1 year and 47% at 5 years. Independent predictors of survival were cerebral infarct type, creatinine elevation, cardiopulmonary bypass time, preoperative intensive care days, postoperative awakening time, and postoperative intensive care days. Long-term disability was moderate to severe in 69%.

Conclusions. Stroke after cardiac surgery has profound repercussions that are independently related to infarct type and clinical factors. These data are essential for clinical decision making and prognosis determination.


Related Article

Invited commentary
Timothy J. Gardner
Ann. Thorac. Surg. 2001 72: 1201-1202. [Extract] [Full Text] [PDF]



This article has been cited by other articles:


Home page
Ann. Thorac. Surg.Home page
I. Aleksic, S.-P. Sommer, E. Kottenberg-Assenmacher, V. Lange, C. Schimmer, M. Oezkur, R. G. Leyh, and A. Gorski
Cardiac operations in the presence of meningioma.
Ann. Thorac. Surg., October 1, 2009; 88(4): 1264 - 1268.
[Abstract] [Full Text] [PDF]


Home page
Ann. Thorac. Surg.Home page
T. C. Lisle, K. M. Barrett, L. M. Gazoni, B. R. Swenson, C. D. Scott, A. Kazemi, J. A. Kern, B. B. Peeler, I. L. Kron, and K. C. Johnston
Timing of Stroke After Cardiopulmonary Bypass Determines Mortality
Ann. Thorac. Surg., May 1, 2008; 85(5): 1556 - 1563.
[Abstract] [Full Text] [PDF]


Home page
Eur. J. Cardiothorac. Surg.Home page
D. L. Ngaage, M. E. Cowen, S. Griffin, L. Guvendik, and A. R. Cale
Early neurological complications after coronary artery bypass grafting and valve surgery in octogenarians
Eur. J. Cardiothorac. Surg., April 1, 2008; 33(4): 653 - 659.
[Abstract] [Full Text] [PDF]


Home page
Ann. Thorac. Surg.Home page
F. Filsoufi, P. B. Rahmanian, J. G. Castillo, D. Bronster, and D. H. Adams
Incidence, Topography, Predictors and Long-Term Survival After Stroke in Patients Undergoing Coronary Artery Bypass Grafting
Ann. Thorac. Surg., March 1, 2008; 85(3): 862 - 870.
[Abstract] [Full Text] [PDF]


Home page
J. Thorac. Cardiovasc. Surg.Home page
J. Schoof, W. Lubahn, M. Baeumer, R. Kross, C.-W. Wallesch, A. Kozian, C. Huth, and M. Goertler
Impaired cerebral autoregulation distal to carotid stenosis/occlusion is associated with increased risk of stroke at cardiac surgery with cardiopulmonary bypass
J. Thorac. Cardiovasc. Surg., September 1, 2007; 134(3): 690 - 696.
[Abstract] [Full Text] [PDF]


Home page
Anesth. Analg.Home page
N. A. Nussmeier, W. Cheng, M. Marino, T. Spata, S. Li, G. Daniels, T. Clark, and W. K. Vaughn
Temperature During Cardiopulmonary Bypass: The Discrepancies Between Monitored Sites
Anesth. Analg., December 1, 2006; 103(6): 1373 - 1379.
[Abstract] [Full Text] [PDF]


Home page
StrokeHome page
R. F. Gottesman, P. M. Sherman, M. A. Grega, D. M. Yousem, L. M. Borowicz Jr, O. A. Selnes, W. A. Baumgartner, and G. M. McKhann
Watershed Strokes After Cardiac Surgery: Diagnosis, Etiology, and Outcome
Stroke, September 1, 2006; 37(9): 2306 - 2311.
[Abstract] [Full Text] [PDF]


Home page
Ann. Thorac. Surg.Home page
T. F. Floyd, P. N. Shah, C. C. Price, F. Harris, S. J. Ratcliffe, M. A. Acker, J. E. Bavaria, H. Rahmouni, B. Kuersten, S. Wiegers, et al.
Clinically Silent Cerebral Ischemic Events After Cardiac Surgery: Their Incidence, Regional Vascular Occurrence, and Procedural Dependence
Ann. Thorac. Surg., June 1, 2006; 81(6): 2160 - 2166.
[Abstract] [Full Text] [PDF]


Home page
Arch NeurolHome page
P. Khatri and S. E. Kasner
Ischemic strokes after cardiac catheterization: opportune thrombolysis candidates?
Arch Neurol, June 1, 2006; 63(6): 817 - 821.
[Abstract] [Full Text] [PDF]


Home page
StrokeHome page
G. M. McKhann, M. A. Grega, L. M. Borowicz Jr, W. A. Baumgartner, and O. A. Selnes
Stroke and Encephalopathy After Cardiac Surgery: An Update
Stroke, February 1, 2006; 37(2): 562 - 571.
[Abstract] [Full Text] [PDF]


Home page
Ann. Thorac. Surg.Home page
R. A. Baker, L. J. Hallsworth, and J. L. Knight
Stroke After Coronary Artery Bypass Grafting
Ann. Thorac. Surg., November 1, 2005; 80(5): 1746 - 1750.
[Abstract] [Full Text] [PDF]


Home page
Eur. J. Cardiothorac. Surg.Home page
S. C. Knipp, N. Matatko, M. Schlamann, H. Wilhelm, M. Thielmann, M. Forsting, H. C. Diener, and H. Jakob
Small ischemic brain lesions after cardiac valve replacement detected by diffusion-weighted magnetic resonance imaging: relation to neurocognitive function
Eur. J. Cardiothorac. Surg., July 1, 2005; 28(1): 88 - 96.
[Abstract] [Full Text] [PDF]


Home page
SEMIN CARDIOTHORAC VASC ANESTHHome page
K. Prasongsukarn and M. A. Borger
Reducing Cerebral Emboli During Cardiopulmonary Bypass
Seminars in Cardiothoracic and Vascular Anesthesia, June 1, 2005; 9(2): 153 - 158.
[Abstract] [PDF]


Home page
SEMIN CARDIOTHORAC VASC ANESTHHome page
R. C. Groom and Cardiovascular Disease Study Group
A Systematic Approach to the Understanding and Redesigning of Cardiopulmonary Bypass
Seminars in Cardiothoracic and Vascular Anesthesia, June 1, 2005; 9(2): 159 - 161.
[Abstract] [PDF]


Home page
J. Am. Soc. Nephrol.Home page
B. G. Loef, A. H. Epema, T. D. Smilde, R. H. Henning, T. Ebels, G. Navis, and C. A. Stegeman
Immediate Postoperative Renal Function Deterioration in Cardiac Surgical Patients Predicts In-Hospital Mortality and Long-Term Survival
J. Am. Soc. Nephrol., January 1, 2005; 16(1): 195 - 200.
[Abstract] [Full Text] [PDF]


Home page
ChestHome page
D. E. Singer, G. W. Albers, J. E. Dalen, A. S. Go, J. L. Halperin, and W. J. Manning
Antithrombotic Therapy in Atrial Fibrillation: The Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy
Chest, September 1, 2004; 126(3_suppl): 429S - 456S.
[Abstract] [Full Text] [PDF]


Home page
Ann. Thorac. Surg.Home page
D. J. Durand, B. A. Perler, G. S. Roseborough, M. A. Grega, L. M. Borowicz Jr, W. A. Baumgartner, and D. D. Yuh
Mandatory versus selective preoperative carotid screening: a retrospective analysis
Ann. Thorac. Surg., July 1, 2004; 78(1): 159 - 166.
[Abstract] [Full Text] [PDF]


Home page
PerfusionHome page
R C Groom, D S Likosky, R J Forest, G T O'Connor, J R Morton, C S Ross, C Clark, and R Kramer
A model for cardiopulmonary bypass redesign
Perfusion, July 1, 2004; 19(4): 257 - 261.
[Abstract] [PDF]


Home page
StrokeHome page
E. Stolz, T. Gerriets, A. Kluge, W.-P. Klovekorn, M. Kaps, and G. Bachmann
Diffusion-Weighted Magnetic Resonance Imaging and Neurobiochemical Markers After Aortic Valve Replacement: Implications for Future Neuroprotective Trials?
Stroke, April 1, 2004; 35(4): 888 - 892.
[Abstract] [Full Text] [PDF]


Home page
Eur. J. Cardiothorac. Surg.Home page
R. Motallebzadeh, R. Kanagasabay, M. Bland, J. C. Kaski, and M. Jahangiri
S100 protein and its relation to cerebral microemboli in on-pump and off-pump coronary artery bypass surgery
Eur. J. Cardiothorac. Surg., March 1, 2004; 25(3): 409 - 414.
[Abstract] [Full Text] [PDF]


Home page
Eur. J. Cardiothorac. Surg.Home page
G. D'Ancona, J. I. S. de Ibarra, R. Baillot, P. Mathieu, D. Doyle, J. Metras, D. Desaulniers, and F. Dagenais
Determinants of stroke after coronary artery bypass grafting
Eur. J. Cardiothorac. Surg., October 1, 2003; 24(4): 552 - 556.
[Abstract] [Full Text] [PDF]


Home page
Ann. Thorac. Surg.Home page
M. Nakajima, K. Tsuchiya, K. Kanemaru, H. Yamazaki, H. Koizumi, S. Nakano, H. Inoue, Y. Naito, and E. Mizutani
Subdural hemorrhagic injury after open heart surgery
Ann. Thorac. Surg., August 1, 2003; 76(2): 614 - 615.
[Abstract] [Full Text] [PDF]


Home page
J. Thorac. Cardiovasc. Surg.Home page
H. B. Hangler, G. Nagele, M. Danzmayr, L. Mueller, E. Ruttmann, G. Laufer, and J. Bonatti
Modification of surgical technique for ascending aortic atherosclerosis: impact on stroke reduction in coronary artery bypass grafting
J. Thorac. Cardiovasc. Surg., August 1, 2003; 126(2): 391 - 400.
[Abstract] [Full Text] [PDF]


Home page
Ann. Thorac. Surg.Home page
R. Sharony, E. A. Grossi, P. C. Saunders, C. F. Schwartz, G. B. Ciuffo, F. G. Baumann, J. Delianides, R. M. Applebaum, G. H. Ribakove, A. T. Culliford,, et al.
Aortic valve replacement in patients with impaired ventricular function
Ann. Thorac. Surg., June 1, 2003; 75(6): 1808 - 1814.
[Abstract] [Full Text] [PDF]


Home page
Ann. Thorac. Surg.Home page
J. Bucerius, J. F. Gummert, M. A. Borger, T. Walther, N. Doll, J. F. Onnasch, S. Metz, V. Falk, and F. W. Mohr
Stroke after cardiac surgery: a risk factor analysis of 16,184 consecutive adult patients
Ann. Thorac. Surg., February 1, 2003; 75(2): 472 - 478.
[Abstract] [Full Text] [PDF]


Home page
Ann. Thorac. Surg.Home page
P. Johnsson, M. Backstrom, C. Bergh, H. Jonsson, C. Luhrs, and C. Alling
Increased S100B in blood after cardiac surgery is a powerful predictor of late mortality
Ann. Thorac. Surg., January 1, 2003; 75(1): 162 - 168.
[Abstract] [Full Text] [PDF]


Home page
EuropaceHome page
C. C. de Cock, C. M. C. van Campen, O. Kamp, and C. A. Visser
Successful percutaneous extraction of an inadvertently placed left ventricular pacing lead
Europace, January 1, 2003; 5(2): 195 - 197.
[Abstract] [PDF]


Home page
PerfusionHome page
K. G. Engstrom
The embolic potential of liquid fat in pericardial suction blood, and its elimination
Perfusion, January 1, 2003; 18(1_suppl): 69 - 74.
[Abstract] [PDF]


Home page
Anesth. Analg.Home page
W. Y. Thong, A. G. Strickler, S. Li, E. E. Stewart, C. L. Collier, W. K. Vaughn, and N. A. Nussmeier
Hyperthermia in the Forty-Eight Hours After Cardiopulmonary Bypass
Anesth. Analg., December 1, 2002; 95(6): 1489 - 1495.
[Abstract] [Full Text] [PDF]


Home page
SEMIN CARDIOTHORAC VASC ANESTHHome page
D. Bainbridge and D. Cheng
Initial Perioperative Care of the Cardiac Surgical Patient
Seminars in Cardiothoracic and Vascular Anesthesia, September 1, 2002; 6(3): 229 - 236.
[Abstract] [PDF]


Home page
Arch NeurolHome page
R. J. Wityk and L. Restrepo
Cardiac Surgery and Magnetic Resonance Imaging of the Brain
Arch Neurol, July 1, 2002; 59(7): 1074 - 1076.
[Full Text] [PDF]


Home page
SEMIN CARDIOTHORAC VASC ANESTHHome page
B. Krishnadasan, C. R. Hampton, J. Griscavage-Ennis, R. J. Dabal, and E. D. Verrier
Molecular Mechanisms of Neurologic Injury Following Cardiopulmonary Bypass
Seminars in Cardiothoracic and Vascular Anesthesia, March 1, 2002; 6(1): 43 - 53.
[Abstract] [PDF]




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 2001 by The Society of Thoracic Surgeons.