ATS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Fang, D.
Right arrow Articles by Zhang, D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Fang, D.
Right arrow Articles by Zhang, D.
Related Collections
Right arrow Lung - cancer

Ann Thorac Surg 2001;72:1155-1159
© 2001 The Society of Thoracic Surgeons

Original article: general thoracic

Results of surgical resection of patients with primary lung cancer: a retrospective analysis of 1,905 cases

Dekang Fang, MDa, Dawei Zhang, MDa, Guojun Huang, MDa, Rugang Zhang, MDa, Liangjun Wang, MDa, Dechao Zhang, MDa

a Department of Thoracic Surgery, Cancer Institute (Hospital), Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, People's Republic of China

Accepted for publication May 29, 2001.

Address reprint requests to Dr Fang, Department of Thoracic Surgery, Cancer Institute (Hospital), Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, People’s Republic of China
e-mail: dekang{at}public3.bta.net.cn

Background. Surgical resection, combined therapies, and lymphadenectomy are extensively utilized in the treatment of patients with lung cancer. In the present study, we summarized the clinical data of patients with primary lung cancer after surgical resection alone or combined with adjuvant therapy, and evaluate the main factors influencing long-term survival.

Methods. A retrospective review of 1,905 consecutive patients with primary lung cancer treated at the Cancer Institute of the Chinese Academy of Medical Sciences from March 1961 through December 1995 was performed. Statistical analysis was done using STATA software. The survival rate was estimated using the life-table method. Survival differences were performed using the log-rank test. The modified 1997 TNM staging system was used.

Results. There was a 12.28% morbidity rate and a 1.31% hospital mortality in our series. The 5-year survival rate for the complete resection was 49.5% and for the palliative resection 18.8% (p < 0.01). The 5-year survival rate was 72.0% in stage IA and 61.0% in stage IB (p < 0.05), 32.9% in stage IIA and 34.5% in stage IIB, 22.6% in stage IIIA and 15.9% in stage IIIB (p < 0.05), and 7.1% in stage IV.

Conclusions. Multiple factors influence the long-term survival of patients with primary lung cancer after surgery. They include TNM staging, the extent of surgical resection (complete or palliative), resection margin (positive or negative), pathologic type of tumors, and type of resection.




This article has been cited by other articles:


Home page
 J. Thorac. Cardiovasc. Surg.Home page
K. Aokage, G. Ishii, K. Nagai, O. Kawai, Y. Naito, T. Hasebe, M. Nishimura, J. Yoshida, and A. Ochiai
Intrapulmonary metastasis in resected pathologic stage IIIB non small cell lung cancer: Possible contribution of aerogenous metastasis to the favorable outcome
J. Thorac. Cardiovasc. Surg., August 1, 2007; 134(2): 386 - 391.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
K. L. Uy, G. Darling, W. Xu, Q.-L. Yi, M. De Perrot, A. F. Pierre, T. K. Waddell, M. R. Johnston, A. Bezjak, F. A. Shepherd, et al.
Improved results of induction chemoradiation before surgical intervention for selected patients with stage IIIA-N2 non-small cell lung cancer
J. Thorac. Cardiovasc. Surg., July 1, 2007; 134(1): 188 - 193.
[Abstract] [Full Text] [PDF]

Home page
 Clin. Cancer Res.Home page
J. E. Larsen, S. J. Pavey, L. H. Passmore, R. V. Bowman, N. K. Hayward, and K. M. Fong
Gene Expression Signature Predicts Recurrence in Lung Adenocarcinoma
Clin. Cancer Res., May 15, 2007; 13(10): 2946 - 2954.
[Abstract] [Full Text] [PDF]

Home page
 ThoraxHome page
T-E Strand, H Rostad, B Moller, and J Norstein
Survival after resection for primary lung cancer: a population based study of 3211 resected patients
Thorax, August 1, 2006; 61(8): 710 - 715.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
H. Rostad, T.-E. Strand, A. Naalsund, O. Talleraas, and J. Norstein
Lung cancer surgery: the first 60 days. A population-based study.
Eur. J. Cardiothorac. Surg., May 1, 2006; 29(5): 824 - 828.
[Abstract] [Full Text] [PDF]

Home page
 Clin. Cancer Res.Home page
J. L. Mulshine
Clinical Issues in the Management of Early Lung Cancer
Clin. Cancer Res., July 1, 2005; 11(13): 4993s - 4998s.
[Abstract] [Full Text] [PDF]

Home page
 ANN INTERN MEDHome page
L. L. Humphrey, S. Teutsch, and M. Johnson
Lung Cancer Screening with Sputum Cytologic Examination, Chest Radiography, and Computed Tomography: An Update for the U.S. Preventive Services Task Force
Ann Intern Med, May 4, 2004; 140(9): 740 - 753.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
E. Martinod, J. F. Azorin, D. Sadoun, M.-D. Destable, P. Le Toumelin, E. Longchampt, M. Kambouchner, L. Guillevin, and D. Valeyre
Surgical resection of lung cancer in patients with underlying interstitial lung disease
Ann. Thorac. Surg., October 1, 2002; 74(4): 1004 - 1007.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 2001 by The Society of Thoracic Surgeons.