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Ann Thorac Surg 2001;72:416-423
© 2001 The Society of Thoracic Surgeons


Original article: cardiovascular

Outcomes of intraoperative device closure of muscular ventricular septal defects

Mataichi Okubo, MDa, Lee N. Benson, MD, FRCPCa, David Nykanen, MD, FRCPCa, Anthony Azakie, MDb, Glen Van Arsdell, MD, FRCSb, John Coles, MD, FRCSb, William G. Williams, MD, FRCSb

a Department of Pediatrics and Surgery, The Hospital For Sick Children, The University of Toronto School of Medicine, Toronto, Ontario, Canada
b Division of Cardiology and Cardiovascular Surgery, The Hospital For Sick Children, The University of Toronto School of Medicine, Toronto, Ontario, Canada

Accepted for publication May 9, 2001.

Address reprint requests to Dr Benson, Division of Cardiology, The Hospital For Sick Children, 555 University Ave, Toronto, Ontario, Canada, M5G 1X8
e-mail: benson{at}sickkids.on.ca

Background. The surgical management of muscular ventricular septal defects (mVSD) in the small infant is a challenge particularly when multiple and associated with complex cardiac lesions. Devices for percutaneous implantation have the advantage of ease of placement and for the double umbrella designs a wide area of coverage. We reviewed our experience and clinical outcomes of intraoperative mVSD device closure for such defects in small infants.

Methods. Since October 1989, intraoperative VSD device closure was a component of the surgical strategy in 14 consecutive patient implants (median age, 5.5 months; range, 3 to 11 kg), whose defects were thought difficult to approach using conventional techniques. Nine patients had associated complex cardiac lesions, 10 multiple mVSDs, and 4 patients had a previous pulmonary artery banding.

Results. There were 2 early deaths, 1 in a severely ill child who preoperatively had pulmonary hypertension and left ventricular failure and another in a patient with a hypoplastic left heart. Mean pulmonary to systemic flow ratio before device insertion was 3.5:1. Complete closure was achieved in 5 patients and clinically insignificant residual shunts persisted in 7. In 2 infants with significant residual lesions concomitant pulmonary artery banding was required. Postoperative mean pulmonary to systemic flow ratio was 1.7:1. In follow-up of the 12 surviving infants (mean, 41 months), 8 had complete closure and 3 persistent residual shunts. One patient with no residual shunting required heart transplantation for progressive ventricular failure 9 years after operation. All devices were well positioned on postoperative echocardiograms. There was 1 late death due to aspiration in a patient with a tiny residual shunt.

Conclusions. Infants requiring operative intervention with mVSDs are difficult to manage and have an increased mortality and morbidity. Intraoperative VSD device placement for closure of mVSDs is feasible, can avoid ventriculotomy, division of intracardiac muscle bands, and is ideally suited for the neonate or infant.




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