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Ann Thorac Surg 2001;72:272-274
© 2001 The Society of Thoracic Surgeons


Case report

Nitric oxide for the treatment of postpneumonectomy pulmonary edema

David G. Rabkin, MDa, Robert N. Sladen, MBChBb, Angela DeMango, MDc, Kenneth M. Steinglass, MDa, Daniel J. Goldstein, MDa a Department of Surgery, Columbia University, College of Physicians and Surgeons, New York, New York, USA
b Department of Anesthesiology, Columbia University, College of Physicians and Surgeons, New York, New York, USA
c Department of Medicine, Columbia University, College of Physicians and Surgeons, New York, New York, USA

Accepted for publication June 27, 2000.

Address reprint requests to Dr Goldstein, Department of Cardiothoracic Surgery, Newark Beth Israel Medical Center, 201 Lyons Ave, Newark, NJ 07112
e-mail: dgoldstein{at}sbhcs.com

Inhaled nitric oxide, a selective pulmonary vasodilator, has been used to improve arterial oxygenation in adult respiratory distress syndrome. To our knowledge, it has not been successfully used to treat this syndrome after major lung resection. We used nitric oxide to treat postpneumonectomy pulmonary edema with immediate and sustained improvement in oxygenation. The patient was successfully weaned from nitric oxide and extubated after 3 days of supportive therapy.




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