HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Author home page(s): Mark S. Allen Daniel L. Miller Claude Deschamps Victor F. Trastek Peter C. Pairolero Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Visbal, A. L. Articles by Pairolero, P. C. Search for Related Content PubMed PubMed Citation Articles by Visbal, A. L. Articles by Pairolero, P. C. Related Collections Esophagus - cancer Related Article

Ann Thorac Surg 2001;71:1803-1808
© 2001 The Society of Thoracic Surgeons

---

Original article: general thoracic

Ivor Lewis esophagogastrectomy for esophageal cancer

^a Division of General Thoracic Surgery, Mayo Clinic, Rochester, Minnesota, USA
^b Department of Surgery, Mayo Clinic, Scottsdale, Arizona, USA

Accepted for publication February 22, 2001.

Address reprint requests to Dr Allen, Department of Surgery, Mayo Clinic, 200 First St, SW, Rochester, MN 55905
e-mail: allen.mark{at}mayo.edu

Background. To examine the efficacy of the Ivor Lewis esophagogastrectomy for esophageal carcinoma prior to the widespread use of preoperative chemotherapy and irradiation, we reviewed our experience.

Methods. We reexamined the cases of 220 consecutive patients who underwent an Ivor Lewis esophagogastrectomy for esophageal cancer from January 1992 through December 1995.

Results. There were 196 men (89.1%) and 24 women. Median age was 65 years (range, 29 to 85 years). The results of pathological study showed adenocarcinoma in 188 patients (85.5%), squamous cell carcinoma in 31 (14.1%), and leiomyosarcoma in 1 patient (0.5%). Postsurgical staging was as follows: stage 0 in 10 patients, stage I in 19, stage IIa in 38, stage IIb in 28, stage III in 111, and stage IV in 14. The operative mortality rate was 1.4% (3 patients), and complications occurred in 83 patients (37.7%). Follow-up was 98.6% complete. Median survival for operative survivors was 1.9 years (range, 32 days to 8.7 years). The overall 5-year survival rate was 25.2%; it was 80% for patients in stage 0, 94.4% for those in stage I, 36.0% for those in stage IIa, 14.3% for patients in stage IIb, 10% for those in stage III and 0% for patients in stage IV.

Conclusions. Ivor Lewis esophagogastrectomy for esophageal cancer is a safe operation. Long-term survival is stage dependent. The low survival associated with advanced cancers should stimulate the search for effective neoadjuvant therapy.

Related Article

Invited commentary

Alex G. Little
Ann. Thorac. Surg. 2001 71: 1808. [Extract] [Full Text] [PDF]

This article has been cited by other articles:

				A. Pennathur and J. D. Luketich Resection for Esophageal Cancer: Strategies for Optimal Management Ann. Thorac. Surg., February 1, 2008; 85(2): S751 - S756. [Abstract] [Full Text] [PDF]

				F. Banki, R. J. Mason, D. Oh, J. A. Hagen, S. R. DeMeester, J. C. Lipham, K. Tanaka, K. D. Danenberg, W. N. Yacoub, P. V. Danenberg, et al. Plasma DNA as a Molecular Marker for Completeness of Resection and Recurrent Disease in Patients With Esophageal Cancer Arch Surg, June 1, 2007; 142(6): 533 - 539. [Abstract] [Full Text] [PDF]

				T. J. Kim, K. H. Lee, Y. H. Kim, S. W. Sung, S. Jheon, S.-k. Cho, and K. W. Lee Postoperative Imaging of Esophageal Cancer: What Chest Radiologists Need to Know RadioGraphics, March 1, 2007; 27(2): 409 - 429. [Abstract] [Full Text] [PDF]

				K. R. Shen, S. D. Cassivi, C. Deschamps, M. S. Allen, F. C. Nichols III, W. S. Harmsen, and P. C. Pairolero Surgical treatment of tumors of the proximal stomach with involvement of the distal esophagus: A 26-year experience with Siewert type III tumors J. Thorac. Cardiovasc. Surg., October 1, 2006; 132(4): 755 - 762. [Abstract] [Full Text] [PDF]

				C. Alexiou, O. A. Khan, E. Black, M. L. Field, P. Onyeaka, L. Beggs, J. P. Duffy, and D. F. Beggs Survival after esophageal resection for carcinoma: the importance of the histologic cell type. Ann. Thorac. Surg., September 1, 2006; 82(3): 1073 - 1077. [Abstract] [Full Text] [PDF]

				M.-S. Lu, Y.-H. Liu, Y.-C. Wu, C.-L. Kao, H.-P. Liu, and M.-J. Hsieh Is it safe to perform esophagectomy in esophageal cancer patients combined with liver cirrhosis? Interactive CardioVascular and Thoracic Surgery, October 1, 2005; 4(5): 423 - 425. [Abstract] [Full Text] [PDF]

				P. H. Schipper, S. D. Cassivi, C. Deschamps, D. C. Rice, F. C. Nichols III, M. S. Allen, and P. C. Pairolero Locally Recurrent Esophageal Carcinoma: When is Re-Resection Indicated? Ann. Thorac. Surg., September 1, 2005; 80(3): 1001 - 1006. [Abstract] [Full Text] [PDF]

				K. A. Kesler, P. R. Helft, E. A. Werner, N. P. Jain, J. A. Brooks, J. M. DeWitt, J. K. Leblanc, N. S. Fineberg, L. H. Einhorn, and J. W. Brown A Retrospective Analysis of Locally Advanced Esophageal Cancer Patients Treated With Neoadjuvant Chemoradiation Therapy Followed by Surgery or Surgery Alone Ann. Thorac. Surg., April 1, 2005; 79(4): 1116 - 1121. [Abstract] [Full Text] [PDF]

				J. A. Crestanello, C. Deschamps, S. D. Cassivi, F. C. Nichols III, M. S. Allen, C. Schleck, and P. C. Pairolero Selective management of intrathoracic anastomotic leak after esophagectomy J. Thorac. Cardiovasc. Surg., February 1, 2005; 129(2): 254 - 260. [Abstract] [Full Text] [PDF]

				B. Z. Atkins, A. S. Shah, K. A. Hutcheson, J. H. Mangum, T. N. Pappas, D. H. Harpole Jr, and T. A. D'Amico Reducing Hospital Morbidity and Mortality Following Esophagectomy Ann. Thorac. Surg., October 1, 2004; 78(4): 1170 - 1176. [Abstract] [Full Text] [PDF]

				R. J. Cerfolio, A. S. Bryant, C. S. Bass, J. R. Alexander, and A. A. Bartolucci Fast Tracking After Ivor Lewis Esophagogastrectomy Chest, October 1, 2004; 126(4): 1187 - 1194. [Abstract] [Full Text] [PDF]

				R. Iyer, N. Wilkinson, T. Demmy, and M. Javle Controversies in the Multimodality Management of Locally Advanced Esophageal Cancer: Evidence-Based Review of Surgery Alone and Combined-Modality Therapy Ann. Surg. Oncol., July 1, 2004; 11(7): 665 - 673. [Abstract] [Full Text] [PDF]

				M. Koshy, N. Esiashvilli, J. C. Landry, C. R. Thomas Jr., and R. H. Matthews Multiple Management Modalities in Esophageal Cancer: Epidemiology, Presentation and Progression, Work-up, and Surgical Approaches Oncologist, April 1, 2004; 9(2): 137 - 146. [Abstract] [Full Text] [PDF]

				C. Mariette, L. Finzi, S. Fabre, J.-M. Balon, I. Van Seuningen, and J.-P. J. Triboulet Factors predictive of complete resection of operable esophageal cancer: a prospective study Ann. Thorac. Surg., June 1, 2003; 75(6): 1720 - 1726. [Abstract] [Full Text] [PDF]

				A. G. Casson, S. C. Evans, A. Gillis, G. A. Porter, P. Veugelers, S. J. Darnton, D. L. Guernsey, and P. Hainaut Clinical implications of p53 tumor suppressor gene mutation and protein expression in esophageal adenocarcinomas: Results of a ten-year prospective study J. Thorac. Cardiovasc. Surg., May 1, 2003; 125(5): 1121 - 1131. [Abstract] [Full Text] [PDF]

				I. Stilidi, M. Davydov, V. Bokhyan, and E. Suleymanov Subtotal esophagectomy with extended 2-field lymph node dissection for thoracic esophageal cancer Eur. J. Cardiothorac. Surg., March 1, 2003; 23(3): 415 - 420. [Abstract] [Full Text] [PDF]

				S. H. Bailey, D. A. Bull, D. H. Harpole, J. J. Rentz, L. A. Neumayer, T. N. Pappas, J. Daley, W. G. Henderson, B. Krasnicka, and S. F. Khuri Outcomes after esophagectomy: a ten-year prospective cohort Ann. Thorac. Surg., January 1, 2003; 75(1): 217 - 222. [Abstract] [Full Text] [PDF]

				I. S. Stilidi Reply to Kotsis et al. Eur. J. Cardiothorac. Surg., February 1, 2002; 21(2): 373 - 374. [Full Text] [PDF]