| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Ann Thorac Surg 2001;71:1503-1507
© 2001 The Society of Thoracic Surgeons
a Oxford Heart Centre, Oxford, United Kingdom
b Department of Cardiovascular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom
Accepted for publication January 20, 2001.
Address reprint requests to Mr Pillai, Oxford Heart Centre, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom
Background. The long saphenous vein remains the commonest conduit used in coronary artery bypass grafting procedures. Surgical trauma during vein harvesting can cause endothelial and smooth muscle injury that has important implications for vein graft longevity. Minimally invasive vein harvesting is advocated to reduce wound morbidity. However, the functional consequences of increased handling and traction, with potentially detrimental effects, remain unknown.
Methods. Forty patients were prospectively randomized into either a minimally invasive (minimal) or traditional (open) saphenous vein harvest group. Smooth muscle contractile function was assessed by responses to potassium chloride and phenylephrine. Endothelial cell function was assessed by responses to serial escalations in concentration of acetylcholine, bradykinin, calcium ionophore, sodium nitroprusside, and N-nitro-L-arginine using isometric tension studies.
Results. Harvest times were similar for both groups. The total incision length in the minimal group was significantly shorter than in the open group. There were no differences in smooth muscle contractions to either receptor-independent or receptor-mediated agonists between the two groups. Similarly, vasorelaxation in response to both endothelium-dependent and endothelium-independent agonists were similar in both groups.
Conclusions. Minimally invasive saphenous vein harvesting is associated with similar medial smooth muscle and endothelial function as open harvesting. These findings suggest that minimally invasive harvesting techniques can be used without major detrimental effects on vascular integrity.
This article has been cited by other articles:
|
|
 |
|
  R. D. Lopes, G. E. Hafley, K. B. Allen, T. B. Ferguson, E. D. Peterson, R. A. Harrington, R. H. Mehta, C. M. Gibson, M. J. Mack, N. T. Kouchoukos, et al. Endoscopic versus Open Vein-Graft Harvesting in Coronary-Artery Bypass Surgery N. Engl. J. Med., July 16, 2009; 361(3): 235 - 244. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. R Vaidyanathan, M. N Sankar, and K. M Cherian Endoscopic vs Conventional Vein Harvesting: a Prospective Analysis Asian Cardiovasc Thorac Ann, April 1, 2008; 16(2): 134 - 138. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. Gongora and T. M. Sundt III Myocardial Revascularization with Cardiopulmonary Bypass Card. Surg. Adult, January 1, 2008; 3(2008): 599 - 632. [Full Text]
|
|
|
|
 |
|
 E. V. Potapov, S. Buz, and R. Hetzer CO2 embolism during minimally invasive vein harvesting Eur. J. Cardiothorac. Surg., May 1, 2007; 31(5): 944 - 945. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. W.Y. Chung, P. Rauniyar, H. Luo, Y. N. Hsiang, C. van Breemen, and E. B. Okon Pharmacologic relaxation of vein grafts is beneficial compared with pressure distention caused by upregulation of endothelial nitric oxide synthase and nitric oxide production J. Thorac. Cardiovasc. Surg., October 1, 2006; 132(4): 925 - 932. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
O. Aziz, T. Athanasiou, and A. Darzi Minimally invasive conduit harvesting: a systematic review Eur. J. Cardiothorac. Surg., March 1, 2006; 29(3): 324 - 333. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 O. Aziz, T. Athanasiou, S. S. Panesar, R. Massey-Patel, O. Warren, J. Kinross, S. Purkayastha, R. Casula, B. Glenville, and A. Darzi Does Minimally Invasive Vein Harvesting Technique Affect the Quality of the Conduit for Coronary Revascularization? Ann. Thorac. Surg., December 1, 2005; 80(6): 2407 - 2414. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. Nasso, A. Anselmi, P. Modugno, and F. Alessandrini Minimally invasive saphenous vein harvesting guided by preoperative echotomography: results of a prospective randomized study Interactive CardioVascular and Thoracic Surgery, October 1, 2005; 4(5): 464 - 468. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. L. Yun, Y. Wu, V. Aharonian, P. Mansukhani, T. A. Pfeffer, C. F. Sintek, G. S. Kochamba, G. Grunkemeier, and S. Khonsari Randomized trial of endoscopic versus open vein harvest for coronary artery bypass grafting: Six-month patency rates J. Thorac. Cardiovasc. Surg., March 1, 2005; 129(3): 496 - 503. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L.P. Perrault, H. Jeanmart, L. Bilodeau, J. Lesperance, J.-F. Tanguay, D. Bouchard, P. Page, and M. Carrier Early quantitative coronary angiography of saphenous vein grafts for coronary artery bypass grafting harvested by means of open versus endoscopic saphenectomy: A prospective randomized trial J. Thorac. Cardiovasc. Surg., May 1, 2004; 127(5): 1402 - 1407. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Z. Davis, D. Garber, S. Clark, H. Roth, V. Bufalino, M. J. Budoff, S. Mao, and H. K. Jacobs Long-term patency of coronary grafts with endoscopically harvested saphenous veins determined by contrast-enhanced electron beam computed tomography J. Thorac. Cardiovasc. Surg., March 1, 2004; 127(3): 823 - 828. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| ANN THORAC SURG | ASIAN CARDIOVASC THORAC ANN | EUR J CARDIOTHORAC SURG |
| J THORAC CARDIOVASC SURG | ICVTS | ALL CTSNet JOURNALS |
