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Jock N. McCullough
Steven L. Lansman
Jan D. Galla
Randall B. Griepp
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Ann Thorac Surg 2001;71:1454-1459
© 2001 The Society of Thoracic Surgeons


Original article: cardiovascular

Favorable outcome after composite valve-graft replacement in patients older than 65 years

Marek P. Ehrlich, MDa, M. Arisan Ergin, MD, PhDa, Jock N. McCullough, MD, PhDa, Steven L. Lansman, MD, PhDa, Jan D. Galla, MD, PhDa, Carol A. Bodian, DrPHb, Randall B. Griepp, MDa

a Department of Cardiothoracic Surgery, The Mount Sinai Medical Center, New York, New York, USA
b Department of Biomathematics, The Mount Sinai Medical Center, New York, New York, USA

Accepted for publication December 13, 2000.

Address reprint requests to Dr Ehrlich, Department of Cardiothoracic Surgery, The Mount Sinai Medical Center, One Gustave L. Levy Pl, Box 1028, New York, NY 10029

Background. Concomitant surgical replacement of the aortic valve and ascending aorta is an ideal treatment for aortic root aneurysms, but there may be hesitation in its use in older patients, despite their known increased risk of rupture. This study was conducted to examine our results in 84 patients older than 65 years undergoing elective aortic root resection with composite valve-graft replacement.

Methods. Eighty-four patients older than 65 years were operated on between June 1987 and August 1998. Median age was 74 years (range, 66 to 89 years), and 57 patients were men. Seventeen patients were undergoing reoperation. Aortic insufficiency was present in 70 patients. Forty-seven patients received a conduit using a bioprosthesis, whereas in 37 a mechanical valved conduit (St. Jude) was used. The ascending aorta alone was replaced in 23 patients; 50 had hemi-arch replacement, and in 11 the entire aortic arch was replaced.

Results. Hospital mortality was 8.3% (7 of 84). Sixteen late deaths (19%) were noted during a median follow-up of 3.2 years (range, 0 to 10 years). Only one late death was aorta-related. The incidence of thrombotic or hemorrhagic complications was 2.1/100 patient-years, with equal frequency for both mechanical and bioprosthetic valves.

Conclusions. We conclude that composite valve-graft replacement in elderly patients results in a low operative mortality, yields excellent long-term survival, and averts fatal aneurysm rupture in this high-risk population.




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