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Ann Thorac Surg 2001;71:1233-1238
© 2001 The Society of Thoracic Surgeons

Original article: cardiovascular

A new predictive model for adverse outcomes after elective thoracoabdominal aortic aneurysm repair

Scott A. LeMaire, MDa, Charles C. Miller, III, PhDa, Lori D. Conklin, MDa, Zachary C. Schmittling, MDa, Cüneyt Köksoy, MDa, Joseph S. Coselli, MDa

a The Michael E. DeBakey Department of Surgery, Baylor College of Medicine, and The Methodist Hospital, Houston, Texas, USA

Address reprint requests to Dr Coselli, 6560 Fannin, #1100, Houston, TX 77030
e-mail: jcoselli{at}bcm.tmc.edu

Presented at the Forty-sixth Annual Meeting of the Southern Thoracic Surgical Association, San Juan, Puerto Rico, Nov 4–6, 1999.

Background. Recent recommendations have emphasized individualized treatment based on balancing a patient’s risk of thoracoabdominal aortic aneurysm rupture with the risk of an adverse outcome after surgical repair. The purpose of this study was to determine which preoperative risk factors currently predict an adverse outcome after elective thoracoabdominal aortic aneurysm repair.

Methods. A single, composite end point termed adverse outcome was defined as the occurrence of any of the following: death within 30 days, death before discharge from the hospital, paraplegia, paraparesis, stroke, or acute renal failure requiring dialysis. A risk factor analysis was performed using data from 1,108 consecutive elective thoracoabdominal aortic aneurysm repairs.

Results. The incidence of an adverse outcome was 13.0% (144 of 1,108 patients); predictors included preoperative renal insufficiency (p = 0.0001), increasing age (p = 0.0035), symptomatic aneurysms (p = 0.020), and extent II aneurysms (p = 0.0001). These risk factors were used to construct an equation that estimates the probability of an adverse outcome for an individual patient.

Conclusions. This new predictive model may assist in decisions regarding elective thoracoabdominal aortic aneurysm operations. For patients who are acceptable candidates, contemporary surgical management provides favorable results.




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