| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Ann Thorac Surg 2001;71:1094-1099
© 2001 The Society of Thoracic Surgeons
a Department of Thoracic and Vascular Surgery, Marie Lannelongue Hospital, Le Plessis Robinson, France
b Unit of Thoracic Surgery, Hôtel-Dieu Hospital, Paris, France
Address reprint requests to Dr Magdeleinat, Service de Chirurgie Thoracique, Hôtel-Dieu, 1, Place du Parvis Notre Dame, 75181 Paris Cedex 04, France
e-mail: pmagde{at}club-internet.fr
Presented at the Poster Session of the Thirty-sixth Annual Meeting of The Society of Thoracic Surgeons, Fort Lauderdale, FL, Jan 31–Feb 2, 2000.
Background. The study was performed to assess prognostic factors in patients with lung cancer invading the chest wall treated by surgery.
Methods. We reviewed retrospectively clinical records of all patients operated on for lung cancer invading chest wall structures between 1984 and 1998.
Results. Two hundred one patients were operated on in this 14-year period. One hundred thirty-seven lobectomies, 55 pneumonectomies, and 9 wedge resections were performed. Extrapleural resection (when invasion was limited to the parietal pleura) and chest wall resection (in the case of invasion of deeper structures) were combined with pulmonary resection in 79 (39%) and 122 (61%) cases, respectively. Pathologic TNM stages were T3N0 in 116 (57.5%) cases, T3N1 in 52 (26%), T3N2 in 27 (13.5%), and T4N0-N1 in 6 (3%). A complete resection was achieved in 167 (83%) cases. Fourteen postoperative deaths (7%) occurred. One hundred thirty-nine patients (74%) underwent postoperative radiotherapy. Actuarial 5-year survival was 24% and 13% after complete and incomplete resection, respectively (p < 0.05). Actuarial 5-year survival after complete resection was 25% in T3N0 patients, 20% in T3N1, and 21% in T3N2. In completely resected patients, univariate and multivariate analyses identified three independent prognostic factors: nodal involvement, depth of parietal invasion, and age. Radiation therapy did not improve survival if a complete resection was possible.
Conclusions. Completeness of resection, nodal involvement, depth of invasion, and age affect survival of patients with lung cancer invading the chest wall. N2 disease should not be considered a contraindication to surgery.
This article has been cited by other articles:
|
|
 |
|
  C. Doddoli, B. D'Journo, F. Le Pimpec-Barthes, A. Dujon, C. Foucault, P. Thomas, and M. Riquet Lung Cancer Invading the Chest Wall: A Plea for En-Bloc Resection but the Need for New Treatment Strategies Ann. Thorac. Surg., December 1, 2005; 80(6): 2032 - 2040. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. A. DiPerna and D. E. Wood Surgical Management of T3 and T4 Lung Cancer Clin. Cancer Res., July 1, 2005; 11(13): 5038s - 5044s. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. Matsuoka, W. Nishio, M. Okada, T. Sakamoto, M. Yoshimura, and N. Tsubota Resection of chest wall invasion in patients with non-small cell lung cancer Eur. J. Cardiothorac. Surg., December 1, 2004; 26(6): 1200 - 1204. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Alifano, G. Benedetti, and R. Trisolini Can Low-Molecular-Weight Heparin Improve the Outcome of Patients With Operable Non-Small Cell Lung Cancer?: An Urgent Call for Research Chest, August 1, 2004; 126(2): 601 - 607. [Full Text] [PDF]
|
|
|
|
|
|
M. Alifano, M. D'Aiuto, P. Magdeleinat, E. Poupardin, A. Chafik, S. Strano, and J. F. Regnard Surgical Treatment of Superior Sulcus Tumors: Results and Prognostic Factors Chest, September 1, 2003; 124(3): 996 - 1003. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W. J. Scott, J. Howington, and B. Movsas Treatment of Stage II Non-small Cell Lung Cancer Chest, January 1, 2003; 123(1_suppl): 188S - 201S. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Akay, A. K. Cangir, H. Kutlay, S. Kavukcu, I. Okten, and S. Yavuzer Surgical treatment of peripheral lung cancer adherent to the parietal pleura Eur. J. Cardiothorac. Surg., October 1, 2002; 22(4): 615 - 620. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. A. Mansour, V. H. Thourani, A. Losken, J. G. Reeves, J. I. Miller Jr, G. W. Carlson, and G. E. Jones Chest wall resections and reconstruction: a 25-year experience Ann. Thorac. Surg., June 1, 2002; 73(6): 1720 - 1726. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. M. Burkhart, M. S. Allen, F. C. Nichols III, C. Deschamps, D. L. Miller, V. F. Trastek, and P. C. Pairolero Results of en bloc resection for bronchogenic carcinoma with chest wall invasion J. Thorac. Cardiovasc. Surg., April 1, 2002; 123(4): 670 - 675. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Deslauriers Current surgical treatment of nonsmall cell lung cancer 2001 Eur. Respir. J., February 1, 2002; 19(35_suppl): 61S - 70s. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Riquet, L. Lang-Lazdunski, F. Le Pimpec-Barthes, A. Dujon, R. Souilamas, C. Danel, and D. Manac'h Characteristics and prognosis of resected T3 non-small cell lung cancer Ann. Thorac. Surg., January 1, 2002; 73(1): 253 - 258. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| ANN THORAC SURG | ASIAN CARDIOVASC THORAC ANN | EUR J CARDIOTHORAC SURG |
| J THORAC CARDIOVASC SURG | ICVTS | ALL CTSNet JOURNALS |
