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Ann Thorac Surg 2001;71:S139-S143
© 2001 The Society of Thoracic Surgeons
a Department of Cardiothoracic Surgery, University of Vienna, Vienna, Austria
b Department of Cardiothoracic Anesthesia and Intensive Care, University of Vienna, Vienna, Austria
c Department of Cardiology, Internal Medicine II, University of Vienna, Vienna, Austria
Address reprint requests to Dr Wieselthaler, Department of Cardiothoracic Surgery, University of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria
e-mail: georg.wieselthaler{at}akh-wien.ac.at
Presented at the Fifth International Conference on Circulatory Support Devices for Severe Cardiac Failure, New York, NY, Sept 15–17, 2000.
Abstract
Background. The bridge to transplantation with pulsatile mechanical assist devices became a standard procedure for patients deteriorating on the waiting list. Recently, continuous flow axial impeller pumps were introduced to clinical application offering new advantages.
Methods. From November 1998 till September 2000, 6 male patients (mean age 53 plus or minus 11 years) with end-stage left heart failure were implanted with a DeBakey ventricular assist device (VAD) axial-flow pump for bridge to transplantation.
Results. Three patients were successfully transplanted after 74, 115, and 117 days, respectively. Two other patients died after 25 and 133 days. One patient is still on the device after 108 days. Because of modification of the implantation technique after the first 2 patients, mean pump-flow within the first 3 weeks was increased from 4.3 ± 0.6 L/min to 6.7 ± 0.3 L/min. Patients were put on regular bicycle-ergometer training and improved their exercise capacities up to a mean maximum oxygen consumption of 20.2 mL/kg/min.
Conclusions. Initial implants of the DeBakey VAD demonstrated support properties comparable to pulsatile pumps but without significant restrictions for extended use.
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H. J. Ankersmit, G. Wieselthaler, B. Moser, S. Gerlitz, G. Roth, G. Boltz-Nitulescu, and E. Wolner Transitory immunologic response after implantation of the DeBakey VAD continuous-axial-flow pump J. Thorac. Cardiovasc. Surg., March 1, 2002; 123(3): 557 - 561. [Abstract] [Full Text] [PDF]
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