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Ann Thorac Surg 2001;71:110-116
© 2001 The Society of Thoracic Surgeons


Original article: cardiovascular

Temperature during coronary artery bypass surgery affects quality of life

Parinda Khatri, PhDa, Michael Babyak, PhDa, Narda D. Croughwell, CRNAb, Rebecca Davis, BSa, William D. White, MPHc, Mark F. Newman, MDb, Joseph G. Reves, MDb, Daniel B. Mark, MDc, James A. Blumenthal, PhDa

a Departments of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina USA
b Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina, USA
c Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA

Accepted for publication August 21, 2000.

Address reprint requests to Dr Blumenthal, Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Box 3119, Durham, NC 27710
e-mail: blume003{at}mc.duke.edu

Background. The objective of this study was to examine the effects of temperature on a variety of indices of psychologic adjustment and quality of life.

Methods. A total of 209 patients randomly received normothermic (warm) or hypothermic (cold) conditions during coronary artery bypass surgery (CABS), and a number of physical, social, and psychologic measures were assessed before as well as 6 weeks and 6 months after CABS.

Results. Repeated measures analyses of covariance revealed significant temperature group main effects for anxiety (p = 0.008) and depression (p = 0.039), with the normothermic group obtaining lower anxiety and depression levels than the hypothermic group at both 6 weeks and 6 months after surgery. Additionally, among patients who entered the study with higher depression levels, those in the hypothermic group tended to have higher depression scores at follow-up compared with patients in the normothermic condition (p = 0.012). No temperature group differences were observed on other quality of life indices.

Conclusions. The results of the present study indicate that hypothermic conditions during CABS are associated with higher levels of emotional distress after CABS than normothermic conditions, particularly for patients with greater stress to begin with.




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