ATS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Online Discussion
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Kilger, E.
Right arrow Articles by Frey, L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kilger, E.
Right arrow Articles by Frey, L.

Ann Thorac Surg 2000;70:2023-2028
© 2000 The Society of Thoracic Surgeons

Original article: cardiovascular

Markers of myocardial ischemia after minimally invasive and conventional coronary operation

Erich Kilger, MDa, Bodo Pichler, MDa, Florian Weis, MDa, Alwin Goetz, PhDa, Peter Lamm, MDb, Albert Schütz, MD, PhDb, Dieter Muehlbayer, MDc, Lorenz Frey, MDa

a Department of Anesthesiology, Ludwig-Maximilian-University of Munich, Munich, Germany
b Department of Cardiac Surgery, Ludwig-Maximilian-University of Munich, Munich, Germany
c Department of Clinical Chemistry, Ludwig-Maximilian-University of Munich, Munich, Germany

Accepted for publication May 4, 2000.

Address reprint requests to Dr Kilger, Department of Anesthesiology, Ludwig-Maximilian-University of Munich, Klinikum Grosshadern, Marchioninistrasse 15, 81377 Munich, Germany
e-mail: erichkilger{at}ana.med.uni-muenchen.de

Background. The purpose of this study was to evaluate the course of serum markers of myocardial tissue damage after two different types of minimally invasive coronary surgical procedures (MICS) as compared with conventional coronary artery bypass grafting (CABG).

Methods. We enrolled 87 patients with one- or two- vessel disease scheduled for one of the three procedures: minimally invasive direct coronary artery bypass grafting (MIDCABG) by lateral thoracotomy (n = 29), the OCTOPUS method by median sternotomy (n = 27), and CABG (n = 31). Creatine kinase activity (CK), creatine kinase MB activity (CK-MB act), creatine kinase MB mass concentration (CK-MB mass), myoglobin concentration (MG), and cardiac troponin I concentration (cTnI) were measured perioperatively until the second postoperative day.

Results. Creatine kinase-MB, CK-MB mass, and cTnI were significantly higher after CABG and were nearly maintained within the normal range in MICS. Creatine kinase and MG were significantly lower in the OCTOPUS group than in the MIDCABG or CABG groups.

Conclusions. Minimally invasive coronary surgical procedures cause less myocardial injury than CABG as indicated by specific serum markers. However, higher CK and MG reflect more substantial skeletal muscle trauma during MIDCABG operation compared with Octopus procedures.




This article has been cited by other articles:


Home page
 CirculationHome page
E. L. Hannan, C. Wu, C. R. Smith, R. S.D. Higgins, R. E. Carlson, A. T. Culliford, J. P. Gold, and R. H. Jones
Off-Pump Versus On-Pump Coronary Artery Bypass Graft Surgery: Differences in Short-Term Outcomes and in Long-Term Mortality and Need for Subsequent Revascularization
Circulation, September 4, 2007; 116(10): 1145 - 1152.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
M. J. Racz, E. L. Hannan, O. W. Isom, V. A. Subramanian, R. H. Jones, J. P. Gold, T. J. Ryan, A. Hartman, A. T. Culliford, E. Bennett, et al.
A comparison of short- and long-term outcomes after off-pump and on-pump coronary artery bypass graft surgery with sternotomy
J. Am. Coll. Cardiol., February 18, 2004; 43(4): 557 - 564.
[Abstract] [Full Text] [PDF]

Home page
 ICVTSHome page
J. Vedin, U. Jensen, A. Ericsson, C. Bitkover, S. Samuelsson, F. Bredin, and J. Vaage
Cardiovascular function during the first 24 hours after off pump coronary artery bypass grafting-a prospective, randomized study
Interactive CardioVascular and Thoracic Surgery, December 1, 2003; 2(4): 489 - 494.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
A. Boening, C. Friedrich, J. Hedderich, J. Schoettler, S. Fraund, and J. T. Cremer
Early and medium-term results after on-pump and off-pump coronary artery surgery: a propensity score analysis
Ann. Thorac. Surg., December 1, 2003; 76(6): 2000 - 2006.
[Abstract] [Full Text] [PDF]

Home page
 HeartHome page
R A Archbold and N P Curzen
Off-pump coronary artery bypass graft surgery: the incidence of postoperative atrial fibrillation
Heart, October 1, 2003; 89(10): 1134 - 1137.
[Abstract] [Full Text] [PDF]

Home page
 PerfusionHome page
A. S Wechsler and S. K Brockman
Myocardial protection: an expanding or contracting discipline?
Perfusion, July 1, 2003; 18(4): 213 - 217.
[Abstract] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
J. D. Puskas, W. H. Williams, P. G. Duke, J. R. Staples, K. E. Glas, J. J. Marshall, M. Leimbach, P. Huber, S. Garas, B. H. Sammons, et al.
Off-pump coronary artery bypass grafting provides complete revascularization with reduced myocardial injury, transfusion requirements, and length of stay: A prospective randomized comparison of two hundred unselected patients undergoing off-pump versus conventional coronary artery bypass grafting
J. Thorac. Cardiovasc. Surg., April 1, 2003; 125(4): 797 - 808.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
W. A. Cooper, J. S. Corvera, V. H. Thourani, J. D. Puskas, J. M. Craver, O. M. Lattouf, and R. A. Guyton
Perfusion-assisted direct coronary artery bypass provides early reperfusion of ischemic myocardium and facilitates complete revascularization
Ann. Thorac. Surg., April 1, 2003; 75(4): 1132 - 1139.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
M. Haase, A. Sharma, A. Fielitz, S. Uchino, J. Rocktaeschel, R. Bellomo, L. Doolan, G. Matalanis, A. Rosalion, B. F. Buxton, et al.
On-pump coronary artery surgery versus off-pump exclusive arterial coronary grafting: a matched cohort comparison
Ann. Thorac. Surg., January 1, 2003; 75(1): 62 - 67.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
Y. Louagie, J. Jamart, S. Broka, E. Collard, V. Scavee, and M. Gonzalez
Off-pump coronary artery bypass grafting: a case-matched comparison of hemodynamic outcome
Eur. J. Cardiothorac. Surg., October 1, 2002; 22(4): 552 - 558.
[Abstract] [Full Text] [PDF]

Home page
 HeartHome page
P. P T. de Jaegere and W. J L Suyker
OFF-PUMP CORONARY ARTERY BYPASS SURGERY
Heart, September 1, 2002; 88(3): 313 - 318.
[Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
N.A. Scott, J.L. Knight, B.P. Bidstrup, H. Wolfenden, R.N. Linacre, and G.J. Maddern
Systematic review of beating heart surgery with the Octopus(R) Tissue Stabilizer
Eur. J. Cardiothorac. Surg., May 1, 2002; 21(5): 804 - 817.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
M. Yacoub
Off-Pump Coronary Bypass Surgery: In Search of an Identity
Circulation, October 9, 2001; 104(15): 1743 - 1745.
[Full Text] [PDF]

Home page
 CirculationHome page
D. van Dijk, A. P. Nierich, E. W.L. Jansen, H. M. Nathoe, W. J.L. Suyker, J. C. Diephuis, W.-J. van Boven, C. Borst, E. Buskens, D. E. Grobbee, et al.
Early Outcome After Off-Pump Versus On-Pump Coronary Bypass Surgery: Results From a Randomized Study
Circulation, October 9, 2001; 104(15): 1761 - 1766.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 2000 by The Society of Thoracic Surgeons.