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Ann Thorac Surg 2000;70:2008-2012
© 2000 The Society of Thoracic Surgeons


Original article: cardiovascular

Rapid recovery protocol applied to 5,658 consecutive "on-pump" coronary bypass patients

Eivind Øvrum, MD, PhDa, Geir Tangen, MDa, Carla Schiøtt, PTa, Stein Dragsund, MDa

a Oslo Heart Center, Oslo, Norway

Accepted for publication May 4, 2000.

Address reprint requests to Dr Øvrum, Oslo Heart Center, 32, P O Box 2684 St. Hanshaugen, 0131 Oslo, Norway
e-mail: eivind.ovrum{at}hjertesentevet.no

Background. Increasing hospital costs, restricted resources, and new surgical strategies have stimulated effectiveness of all routines in cardiac surgery. Over a 10-year period, 5,658 consecutive patients undergoing coronary artery bypass grafting followed a protocol aiming at short postoperative intubation times and rapid physical rehabilitation.

Methods. The patients were prepared for rapid recovery, emphasizing (1) preoperative education and respiratory training, (2) low-dose fentanyl anesthesia, (3) limited ischemic times and pump times, (4) mild hypothermia and rewarming to a rectal temperature of 36°C, (5) restricted use of extended monitoring, (6) autologous blood salvage to avoid allogeneic blood transfusions, and (7) active physical training from postoperative day 1. All in-hospital data relevant to these steps were prospectively stored in a database.

Results. The median extubation time after arrival in the intensive care unit was 1.5 hours (0 to 320 hours). More than 99% of the patients were extubated within 5 hours. Sixty-two patients (1.1%) were reintubated and ventilated for a median of 24 hours (1 to 430 hours), mostly due to resternotomy for bleeding or cardiopulmonary decompensation. In total, 5,594 patients (98.9%) were able to sit in a chair the first postoperative day. Within the fourth postoperative day, 82.5% were able to move freely in the hospital area and were in fact physically fit for hospital discharge. Allogeneic blood products were given to 3.9% of the patients. Twenty-three patients (0.41%) died in-hospital.

Conclusions. With the application of a protocol for rapid physical recovery in patients undergoing "on-pump" coronary artery bypass grafting, extubation within 1 to 2 hours was safe and feasible in most patients. After 5 hours, 99.3% of the patients were extubated, with a reintubation rate of 1.1%. More than 80% of the patients were fully physically mobile within 4 days after the operation.




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