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Ann Thorac Surg 2000;70:1615-1619
© 2000 The Society of Thoracic Surgeons
a Department of Surgery, Osaka Prefectural Habikino Hospital, Osaka, Japan
b Department of Surgery, Course of Interventional Medicine (E1), Osaka University Graduate School of Medicine, Osaka, Japan
c Department of Surgery, National Kinki Central Hospital for Chest Diseases, Osaka, Japan
d Department of Surgery, Toneyama National Hospital, Osaka, Japan
Address reprint requests to Dr Miyoshi, Department of Surgery, Course of Interventional Medicine (E1), Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan
e-mail: miyoshi{at}surg1.med.osaka-u.ac.jp
Background. Operation with combined chemotherapy has been recently recommended for very early stage of small cell lung cancer without lymph node metastasis.
Methods. A retrospective study was undertaken in 91 patients who had undergone pulmonary resection for small cell lung cancer according to the new international staging system.
Results. The 5-year overall probability of survival was 37.1%. The 5-year survival rate was 100% for p-stage 0, 56.1% for p-stage IA, 30.0% for p-stage IB, 57.1% for p-stage IIA, and 42.9% for p-stage IIB. In the p-stage IA–IIB patients who underwent a complete resection, the 5-year survival rate of the patients treated by operation with chemotherapy was better than that of patients treated by operation alone. In addition, the 5-year survival rate of the patients who had four or more courses of chemotherapy was 80.0%.
Conclusions. These results suggest that operation should be considered for p-stage IA–IIB patients and more than four courses of combined chemotherapy might be desirable in these resectable cases.
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