ATS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Author home page(s):
James W. Frederiksen
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Frederiksen, J. W.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Frederiksen, J. W.

Ann Thorac Surg 2000;70:1434-1443
© 2000 The Society of Thoracic Surgeons

Current review

Cardiopulmonary bypass in humans: bypassing unfractionated heparin

James W. Frederiksen, MDa

a Division of Cardiothoracic Surgery, Department of Surgery, Northwestern University Medical School, Chicago, Illinois, USA

Address reprint requests to Dr Frederiksen, Division of Cardiothoracic Surgery, Department of Surgery, Northwestern University Medical School 251 East Chicago Ave, Suite 1030, Chicago, IL 60611;
e-mail: jwf{at}nwu.edu

Seven anticoagulants besides unfractionated heparin have been used for human cardiopulmonary bypass (CPB), mainly in patients with heparin-induced thrombocytopenia. The collective experience with these alternative anticoagulants provides a perspective on current efforts aimed at improving CPB anticoagulation. Unfortunately, each alternative currently lacks a standard dosing schedule and a reliable method of monitoring the adequacy of its anticoagulant effect during CPB. Most also lack proven antidotes. Thus, unfractionated heparin remains the anticoagulant of choice for standard CPB.




This article has been cited by other articles:


Home page
 SEMIN CARDIOTHORAC VASC ANESTHHome page
A. F. Merry
Focus on Thrombin: Alternative Anticoagulants
Seminars in Cardiothoracic and Vascular Anesthesia, December 1, 2007; 11(4): 256 - 260.
[Abstract] [PDF]

Home page
 Ann. Thorac. Surg.Home page
J. A. Morgan, A. R. Kherani, D. W. Vigilance, F. H. Cheema, N. J. Colletti, D. I. Sahar, K.-M. Jan, D. L. Diuguid, R. Nowygrod, M. C. Oz, et al.
Off-pump right atrial thrombectomy for heparin-induced thrombocytopenia with thrombosis
Ann. Thorac. Surg., August 1, 2003; 76(2): 615 - 617.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
M. Carrier, D. Robitaille, L. P. Perrault, M. Pellerin, P. Page, R. Cartier, and D. Bouchard
Heparin versus danaparoid in off-pump coronary bypass grafting: Results of a prospective randomized clinical trial
J. Thorac. Cardiovasc. Surg., February 1, 2003; 125(2): 325 - 329.
[Abstract] [Full Text] [PDF]

Home page
 PerfusionHome page
W. J DeBois, J. Liu, L. Y Lee, L. N Girardi, C. Mack, A. Tortolani, K. H Krieger, and O W. Isom
Diagnosis and treatment of heparin-induced thrombocytopenia
Perfusion, January 1, 2003; 18(1): 47 - 53.
[Abstract] [PDF]

Home page
 PerfusionHome page
L. K von Segesser, X Mueller, B Marty, J Horisberger, and A Corno
Alternatives to unfractioned heparin for anticoagulation in cardiopulmonary bypass
Perfusion, September 1, 2001; 16(5): 411 - 416.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 2000 by The Society of Thoracic Surgeons.