ATS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Online Discussion
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Author home page(s):
Tommaso Claudio Mineo
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Pompeo, E.
Right arrow Articles by Mineo, T. C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Pompeo, E.
Right arrow Articles by Mineo, T. C.
Related Collections
Right arrowRelated Article

Ann Thorac Surg 2000;70:948-953
© 2000 The Society of Thoracic Surgeons

Original articles: general thoracic

Reduction pneumoplasty versus respiratory rehabilitation in severe emphysema: a randomized study

Eugenio Pompeo, MDa, Mario Marino, MDb, Italo Nofroni, MDc, Giuseppe Matteucci, MDb, Tommaso Claudio Mineo, MD, for the Pulmonary Emphysema Research Groupa,*

a Division of Thoracic Surgery, Tor Vergata University, Rome, Italy
b Division of Pulmonary Medicine and Respiratory Rehabilitation, Ospedale Cartoni, Rocca Priora, Italy
c Department of Experimental Medicine and Pathology, La Sapienza University, Rome, Italy

Address reprint requests to Dr Pompeo, Cattedra di Chirurgia Toracica, Università Tor Vergata, Ospedale S. Eugenio, P.le Umanesimo, 10, 00144 Rome, Italy
e-mail: pompeo{at}med.uniroma2.it

Presented at the Thirty-sixth Annual Meeting of The Society of Thoracic Surgeons, Fort Lauderdale, FL, Jan 31–Feb 2, 2000.

Background. The purpose of the study was to determine in a prospective randomized trial the independent short-term physiologic impact of reduction pneumoplasty (RP) on respiratory rehabilitation (RR).

Methods. Sixty patients eligible for RP were randomly selected by computer to receive either RP (n = 30) or comprehensive RR (n = 30). Pulmonary function tests, analysis of blood gas levels, measurement of respiratory muscle strength (maximal inspiratory and expiratory pressures), 6-minute walk test (6MWT), and incremental treadmill test (ITT), were performed at baseline and at 3 and 6 months.

Results. Two treatment-related deaths occurred after RP and one after RR. At 6 months dyspnea index, maximal inspiratory pressure, 6MWT, ITT, and PaO2 were significantly improved in both groups whereas forced expiratory volume in 1 second and residual volume were significantly improved only in the surgical arm. In addition at 6 months, dyspnea index, 6MWT, maximal ITT, and PaO2 improved significantly more after RP than after RR.

Conclusions. In our study short-term improvements in dyspnea index, oxygenation, inspiratory muscle strength, and exercise capacity occurred after either RP and RR. However dyspnea index, PaO2, and exercise capacity improved more after RP than after RR whereas pulmonary function improved only after RP.


Related Article

Discussion
Ann. Thorac. Surg. 2000 70: 954. [Extract] [Full Text] [PDF]



This article has been cited by other articles:


Home page
 Am. J. Respir. Crit. Care Med.Home page
M. L. Snyder, C. H. Goss, B. Neradilek, N. L. Polissar, Z. Mosenifar, R. A. Wise, A. P. Fishman, J. O. Benditt, and for the National Emphysema Treatment Trial Researc
Changes in Arterial Oxygenation and Self-Reported Oxygen Use after Lung Volume Reduction Surgery
Am. J. Respir. Crit. Care Med., August 15, 2008; 178(4): 339 - 345.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
D. Mineo, V. Ambrogi, L. Frasca, M. E. Cufari, E. Pompeo, and T. C. Mineo
Effects of Lung Volume Reduction Surgery for Emphysema on Glycolipidic Hormones
Chest, July 1, 2008; 134(1): 30 - 37.
[Abstract] [Full Text] [PDF]

Home page
 Proc Am Thorac SocHome page
S. D. Ramsey, S. D. Sullivan, and R. M. Kaplan
Cost-Effectiveness of Lung Volume Reduction Surgery
Proceedings of the ATS, May 1, 2008; 5(4): 406 - 411.
[Abstract] [Full Text] [PDF]

Home page
 Proc Am Thorac SocHome page
E. P. Ingenito, D. E. Wood, and J. P. Utz
Bronchoscopic Lung Volume Reduction in Severe Emphysema
Proceedings of the ATS, May 1, 2008; 5(4): 454 - 460.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
E. Pompeo and T. C. Mineo
Two-Year Improvement in Multidimensional Body Mass Index, Airflow Obstruction, Dyspnea, and Exercise Capacity Index After Nonresectional Lung Volume Reduction Surgery in Awake Patients
Ann. Thorac. Surg., December 1, 2007; 84(6): 1862 - 1869.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
D. E. Wood, R. J. McKenna Jr, R. D. Yusen, D. H. Sterman, D. E. Ost, S. C. Springmeyer, H. X. Gonzalez, M. S. Mulligan, T. Gildea, W. V. Houck, et al.
A multicenter trial of an intrabronchial valve for treatment of severe emphysema
J. Thorac. Cardiovasc. Surg., January 1, 2007; 133(1): 65 - 73.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
T. C. Mineo, E. Pompeo, D. Mineo, V. Ambrogi, D. Ciarapica, and A. Polito
Resting energy expenditure and metabolic changes after lung volume reduction surgery for emphysema.
Ann. Thorac. Surg., October 1, 2006; 82(4): 1205 - 1211.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
K. S. Naunheim, D. E. Wood, Z. Mohsenifar, A. L. Sternberg, G. J. Criner, M. M. DeCamp, C. C. Deschamps, F. J. Martinez, F. C. Sciurba, J. Tonascia, et al.
Long-Term Follow-Up of Patients Receiving Lung-Volume-Reduction Surgery Versus Medical Therapy for Severe Emphysema by the National Emphysema Treatment Trial Research Group
Ann. Thorac. Surg., August 1, 2006; 82(2): 431 - 443.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
M. Tutic, D. Lardinois, S. Imfeld, S. Korom, A. Boehler, R. Speich, K. E. Bloch, E. W. Russi, and W. Weder
Lung-volume reduction surgery as an alternative or bridging procedure to lung transplantation.
Ann. Thorac. Surg., July 1, 2006; 82(1): 208 - 213.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
J. D. Miller, R. A. Malthaner, C. H. Goldsmith, R. Goeree, D. Higgins, P. G. Cox, L. Tan, J. D. Road, and Canadian Lung Volume Reduction Surgery Study
A Randomized Clinical Trial of Lung Volume Reduction Surgery Versus Best Medical Care for Patients With Advanced Emphysema: A Two-Year Study From Canada
Ann. Thorac. Surg., January 1, 2006; 81(1): 314 - 321.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
G. Hillerdal, C.-G. Lofdahl, K. Strom, B.-E. Skoogh, L. Jorfeldt, F. Nilsson, D. Forslund-Stiby, J. Ranstam, E. Gyllstedt, and of the Swedish VOLREM Group
Comparison of Lung Volume Reduction Surgery and Physical Training on Health Status and Physiologic Outcomes: A Randomized Controlled Clinical Trial
Chest, November 1, 2005; 128(5): 3489 - 3499.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
T. C. Mineo, V. Ambrogi, D. Mineo, A. Fabbri, E. Fabbrini, and R. Massoud
Bone Mineral Density Improvement After Lung Volume Reduction Surgery for Severe Emphysema
Chest, June 1, 2005; 127(6): 1960 - 1966.
[Abstract] [Full Text] [PDF]

Home page
 Chronic Respiratory DiseaseHome page
Z J McKeoughl, J A Alison, M S Bayfield, and P T.P Bye
Supported and unsupported arm exercise capacity following lung volume reduction surgery: a pilot study
Chronic Respiratory Disease, April 1, 2005; 2(2): 59 - 65.
[Abstract] [PDF]

Home page
 ChestHome page
R. D. Yusen and B. Littenberg
Integrating Survival and Quality of Life Data in Clinical Trials of Lung Disease: The Case of Lung Volume Reduction Surgery
Chest, April 1, 2005; 127(4): 1094 - 1096.
[Full Text] [PDF]

Home page
 ChestHome page
J. D. Miller, R. L. Berger, R. A. Malthaner, B. R. Celli, C. H. Goldsmith, E. P. Ingenito, D. Higgins, P. Bagley, G. Cox, and C. D. Wright
Lung Volume Reduction Surgery vs Medical Treatment: For Patients With Advanced Emphysema
Chest, April 1, 2005; 127(4): 1166 - 1177.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
T. C. Mineo, E. Pompeo, D. Mineo, P. Rogliani, C. Leonardis, and I. Nofroni
Results of unilateral lung volume reduction surgery in patients with distinct heterogeneity of emphysema between lungs
J. Thorac. Cardiovasc. Surg., January 1, 2005; 129(1): 73 - 79.
[Abstract] [Full Text] [PDF]

Home page
 Chronic Respiratory DiseaseHome page
Z J McKeough,, J A Alison, M S Bayfield, and P. Bye
Reduction in resting energy expenditure following lung volume reduction surgery in subjects with chronic obstructive pulmonary disease
Chronic Respiratory Disease, October 1, 2004; 1(4): 197 - 202.
[Abstract] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
M. Tutic, K. E. Bloch, D. Lardinois, T. Brack, E. W. Russi, and W. Weder
Long-term results after lung volume reduction surgery in patients with {alpha}1-antitrypsin deficiency
J. Thorac. Cardiovasc. Surg., September 1, 2004; 128(3): 408 - 413.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
D. Ost, L. Glassman, A. M. Fein, and P. Marcus
Innovations in Lung Volume Reduction: The Non-Cutting Edge
Chest, July 1, 2004; 126(1): 6 - 9.
[Full Text] [PDF]

Home page
 Eur Respir JHome page
T.C. Mineo, V. Ambrogi, E. Pompeo, S. Elia, D. Mineo, P. Bollero, and I. Nofroni
Impact of lung volume reduction surgery versus rehabilitation on quality of life
Eur. Respir. J., February 1, 2004; 23(2): 275 - 280.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
R. A. Maxfield
New and Emerging Minimally Invasive Techniques for Lung Volume Reduction
Chest, February 1, 2004; 125(2): 777 - 783.
[Abstract] [Full Text] [PDF]

Home page
 Eur Respir JHome page
M. Decramer
Treatment of chronic respiratory failure: lung volume reduction surgery versus rehabilitation
Eur. Respir. J., November 16, 2003; 22(47_suppl): 47S - 56s.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
K. Jorgensen, E. Houltz, U. Westfelt, F. Nilsson, H. Schersten, and S.-E. Ricksten
Effects of Lung Volume Reduction Surgery on Left Ventricular Diastolic Filling and Dimensions in Patients With Severe Emphysema
Chest, November 1, 2003; 124(5): 1863 - 1870.
[Abstract] [Full Text] [PDF]

Home page
 Eur Respir JHome page
E.W. Russi, K.E. Bloch, and W. Weder
Lung volume reduction surgery: what can we learn from the National Emphysema Treatment Trial?
Eur. Respir. J., October 1, 2003; 22(4): 571 - 573.
[Full Text] [PDF]

Home page
 ThoraxHome page
B F Meyers and G A Patterson
Chronic obstructive pulmonary disease * 10: Bullectomy, lung volume reduction surgery, and transplantation for patients with chronic obstructive pulmonary disease
Thorax, July 1, 2003; 58(7): 634 - 638.
[Abstract] [Full Text] [PDF]

Home page
 NEJMHome page
National Emphysema Treatment Trial Research Group
A Randomized Trial Comparing Lung-Volume-Reduction Surgery with Medical Therapy for Severe Emphysema
N. Engl. J. Med., May 22, 2003; 348(21): 2059 - 2073.
[Abstract] [Full Text] [PDF]

Home page
 NEJMHome page
National Emphysema Treatment Trial Research Group
Cost Effectiveness of Lung-Volume-Reduction Surgery for Patients with Severe Emphysema
N. Engl. J. Med., May 22, 2003; 348(21): 2092 - 2102.
[Abstract] [Full Text] [PDF]

Home page
 ThoraxHome page
R S Goldstein, T R J Todd, G Guyatt, S Keshavjee, T E Dolmage, S van Rooy, B Krip, F Maltais, P LeBlanc, S Pakhale, et al.
Influence of lung volume reduction surgery (LVRS) on health related quality of life in patients with chronic obstructive pulmonary disease
Thorax, May 1, 2003; 58(5): 405 - 410.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
R. D. Yusen, S. S. Lefrak, D. S. Gierada, G. E. Davis, B. F. Meyers, G. A. Patterson, and J. D. Cooper
A Prospective Evaluation of Lung Volume Reduction Surgery in 200 Consecutive Patients
Chest, April 1, 2003; 123(4): 1026 - 1037.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
A. M. Ciccone, B. F. Meyers, T. J. Guthrie, G. E. Davis, R. D. Yusen, S. S. Lefrak, G. A. Patterson, and J. D. Cooper
Long-term outcome of bilateral lung volume reduction in 250 consecutive patients with emphysema
J. Thorac. Cardiovasc. Surg., March 1, 2003; 125(3): 513 - 525.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
E. P. Ingenito, R. L. Berger, A. C. Henderson, J. J. Reilly, L. Tsai, and A. Hoffman
Bronchoscopic Lung Volume Reduction Using Tissue Engineering Principles
Am. J. Respir. Crit. Care Med., March 1, 2003; 167(5): 771 - 778.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
E. P. Ingenito, S. H. Loring, M. L. Moy, S. J. Mentzer, S. J. Swanson, and J. J. Reilly
Physiological characterization of variability in response to lung volume reduction surgery
J Appl Physiol, January 1, 2003; 94(1): 20 - 30.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
T. C. Mineo, V. Ambrogi, E. Pompeo, P. Bollero, D. Mineo, and I. Nofroni
Body weight and nutritional changes after reduction pneumoplasty for severe emphysema: A randomized study
J. Thorac. Cardiovasc. Surg., October 1, 2002; 124(4): 660 - 667.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
K. E. Bloch, C. L. Georgescu, E. W. Russi, and W. Weder
Gain and subsequent loss of lung function after lung volume reduction surgery in cases of severe emphysema with different morphologic patterns
J. Thorac. Cardiovasc. Surg., May 1, 2002; 123(5): 845 - 854.
[Abstract] [Full Text] [PDF]

Home page
 Eur Respir JHome page
E. Marchand, P. De Leyn, G. Gayan-Ramirez, F. Palecek, E. Verbeken, and M. Decramer
Effects of lung volume reduction surgery in hamsters with elastase-induced emphysema
Eur. Respir. J., March 1, 2002; 19(3): 422 - 428.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
T. C. MINEO, E. POMPEO, P. ROGLIANI, M. DAURI, F. TURANI, P. BOLLERO, and N. MAGLIOCCHETTI
Effect of Lung Volume Reduction Surgery for Severe Emphysema on Right Ventricular Function
Am. J. Respir. Crit. Care Med., February 15, 2002; 165(4): 489 - 494.
[Abstract] [Full Text] [PDF]

Home page
 ThoraxHome page
T P Toma, P Goldstraw, and D M Geddes
Lung volume reduction surgery
Thorax, January 1, 2002; 57(1): 5 - 5.
[Full Text] [PDF]

Home page
 NEJMHome page
National Emphysema Treatment Trial Research Group
Patients at High Risk of Death after Lung-Volume-Reduction Surgery
N. Engl. J. Med., October 11, 2001; 345(15): 1075 - 1083.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
R. L. Berger, B. R. Celli, A. L. Meneghetti, P. H. Bagley, C. D. Wright, E. P. Ingenito, A. Gray, and G. L. Snider
Limitations of randomized clinical trials for evaluating emerging operations: the case of lung volume reduction surgery
Ann. Thorac. Surg., August 1, 2001; 72(2): 649 - 657.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
A. F. GELB, R. J. McKENNA Jr., M. BRENNER, J. D. EPSTEIN, and N. ZAMEL
Lung Function 5 yr after Lung Volume Reduction Surgery for Emphysema
Am. J. Respir. Crit. Care Med., June 1, 2001; 163(7): 1562 - 1566.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
A. F. Gelb, R. J. McKenna Jr, and M. Brenner
Expanding Knowledge of Lung Volume Reduction
Chest, May 1, 2001; 119(5): 1300 - 1303.
[Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 2000 by The Society of Thoracic Surgeons.